Synchronous Early Gastric Cancer/Neuroendocrine Tumor Associated with Autoimmune Gastritis Completely Resected with Endoscopic Submucosal Dissection

Abstract

Synchronous early gastric cancer/neuroendocrine tumor (NET) associated with autoimmune gastritis is rare, and its endoscopic and pathological features remain poorly described. Screening esophagogastroduodenoscopy performed on a 71-year-old man revealed a whitish, superficial elevated lesion and a submucosal tumor with redness that appeared slightly centrally depressed. Endoscopic submucosal dissection (ESD) allowed these lesions to be resected with negative margins, and they were diagnosed as tubular adenocarcinoma, well-differentiated type (tub1), pT1a (M) and NET G1, pT1b (SM). To our knowledge, this is the first report describing the endoscopic and pathological findings of synchronous early gastric cancer/NET that was amenable to complete resection with ESD.

Autoimmune Gastritis Accompanied by a Schwannoma Presenting as a Subepithelial Tumor

“…12 Therefore, NETs accompanied by AIG may appear as SETs, occur in various locations, and may hide malignancy when they are <2 cm. [13][14][15][16][17] Table 1 summarizes cases reporting SETs in AIG patients thus far. A schwannoma, confirmed by biopsy, is a benign, asymptomatic tumor that can be discovered incidentally and has a good prognosis.…”