To observe electronic dynamics in atoms, molecules, and condensed matter taking place on an attosecond time scale, next-generation photon science facilities like X-ray free-electron lasers and intense laser beamlines require system-wide attosecondlevel synchronization of dozens of optical and microwave signals up to kilometer distances. Here, we present for the first time a timing synchronization system that can meet the strict timing requirements of such large-scale facilities. We discuss some key enabling technologies including master-laser jitter characterization, local timing synchronization, new designs of attosecond-precision timing/phase detectors, and analyze fundamental noise contributions in nonlinear pulse propagation in fiber links. Finally, a complete 4.7-km laser-microwave network with 950-as timing jitter is realized over tens of hours of continuous operation.