Synchronous multiple oral squamous cell carcinomas: Report of a case

Munde, Anita; Karle, Ravindra; Wankhede, Pranali

doi:10.4103/0976-433x.138767

Cited by 2 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study by Dissanayaka WL et al [ 6], reported 100% male predominance of synchronous SCCs, with no synchronous occurrence in female patients. Contradictory to it, our index case is a female.…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Synchronus Oral Squamous Cell Carcinoma in A Female: A Rare Case Report

Kadam¹

2023

JCOR

View full text Add to dashboard Cite

Worldwide, the number of new cases of lip and oral cavity cancer in both sexes, all age groups in 2020 are around 377713 and the number of deaths in both sexes, all age groups are around 177757. In India, lip and oral cavity cancer ranks at 2nd position with incidence around 10.3%, mortality 8.8% and 5- year prevalence around21.77%. Multiple theories have been put forth describing the multifocal origin of squamous cell carcinoma (SCC) of the oral and aerodigestive tract. “Field Cancerization “is the first theory described in oral squamous cell carcinoma (SCC) which explains the multifocal or synchronous origin of the SCC. Synchronous carcinomas are defined as second neoplasms at the same time or within 6 months period of primary lesions. After that, they are described as metachronous neoplasms. The criteria to describe synchronous tumours were elaborated by Warren and Gates and Moertel et al. “Field Cancerization “theory was explained by widespread epithelial exposure to carcinogens; however, the alternative theory of common clonal origin is now supported by the recent molecular studies. Second Primary Tumours (Synchronous or Metachronous) are usually more aggressive, more resistant, metastasizes early and they require a more aggressive treatment strategy. Hence, their early detection is the crucial step in planning the best possible management. We are reporting an unusual case of synchronous oral squamous cell carcinoma in 58-year-old female who underwent surgery followed by adjuvant treatment after diagnosis.

show abstract

Section: Discussionmentioning

confidence: 98%

“…The criteria to describe synchronous tumors were elaborated by Warren and Gates and Moertel et al [ 6]. "Field Cancerization "theory was explained by widespread epithelial exposure to carcinogens; however, the alternative theory of common clonal origin is now supported by the recent molecular studies [ 7].…”

Section: Introductionmentioning

confidence: 99%

Synchronus Oral Squamous Cell Carcinoma in A Female: A Rare Case Report

Kadam¹

2023

JCOR

View full text Add to dashboard Cite

show abstract

“…Because multiple aggressive CGCs are a common feature of Noonan syndrome, it is included in the differential diagnosis in our case. The absence of symptoms, such as short stature, broad or webbed neck, low set and posteriorly angulated ears, ptosis, hypertelorism, and downward-slanting eyes in the current patient, as well as low intelligence or developmental delay, downward-slanting eyes, ptosis, and pulmonary stenosis, rules out Noonan syndrome [ 5 , 21 , 23 – 25 ].…”

Section: Discussionmentioning

confidence: 99%

“…Paget disease may be associated with malignant tumors, including osteosarcoma, fibrosarcoma, and benign tumors, such as CGCG. Radiographically, a cotton wool appearance and an elevated level of serum alkaline phosphatase and hydroxyproline in urine are noted [ 17 , 23 , 25 – 27 ]. Therefore, Paget disease is also ruled out in our case.…”

Section: Discussionmentioning

confidence: 99%

“…Cherubism is characterized by the appearance of symmetrical, multiquadrant, multilocular, painless, and expansile radiolucent lesions in posterior sections of both jaws in a young age group, typically between the ages of 2 and 7 years. Submandibular lymph node involvement led to swelling and facial fullness in the early stages of the disorder [ 5 , 6 , 23 , 25 , 28 – 30 ]. Cherubism has a similar histological appearance to CCCG, it is distinguished by the presence of eosinophilic perivascular cuffing, and their absence, however, does not rule out cherubism as a diagnosis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Aggressive Multiple Central Giant Cell Granulomas of the Jaws

Mohammadi

Fakhar

Aliasghari

et al. 2023

Case Reports in Dentistry

View full text Add to dashboard Cite

Central giant cell granuloma (CGCG) is considered a benign intraosseous lesion with a varied range of clinical features in two subtypes, including aggressive and non-aggressive lesions. This study presents a 9-year-old boy with multiple bilateral CGCG in the mandible without any systemic disease or specific syndrome. Clinical, radiographic, and histopathological findings demonstrated the aggressive lesions. It is discussed how the differential diagnosis and treatment can be determined based on the patient’s age as well as the size and manner of the lesion.

show abstract

Synchronous multiple oral squamous cell carcinomas: Report of a case

Cited by 2 publications

References 0 publications

Synchronus Oral Squamous Cell Carcinoma in A Female: A Rare Case Report

Synchronus Oral Squamous Cell Carcinoma in A Female: A Rare Case Report

Aggressive Multiple Central Giant Cell Granulomas of the Jaws

Contact Info

Product

Resources

About