Synchronous, primary, diffuse, large b‐cell lymphomas involving the ethmoid sinus and epiglottis: A rare clinical entity

Abstract

Non-Hodgkin's lymphoma (NHL) affecting the ethmoid sinus and epiglottis is uncommon. Furthermore, synchronous NHLs involving the ethmoid sinus and epiglottis are extremely rare and have not been reported previously. This article reports synchronous, primary, diffuse, large B-cell lymphoma (DLBCL) arising in the ethmoid sinus and epiglottis, which was successfully treated by immunochemotherapy. A careful examination of the head and neck is necessary to determine the existence of multiple synchronous primary tumors, because primary synchronous occurrence of DLBCL in the head and neck is unusual and can impact the prognosis adversely.

Primer Sinonasal Diffuse Large B-Cell Lymphoma

“…Ancak primer sinonazal lenfomalar oldukça nadir görülen tümörlerdir ve ekstranodal non-Hodgkin lenfomaların yaklaşık %2'sini oluşturmaktadırlar. 3,4 Dulguerov ve ark., son 40 yıl boyunca burun ve paranazal sinüs maligniteleri olan hastaları taramışlar ve 220 hastalık seride lenfoma hastası saptamamışlardır. 5 Non-Hodgkin lenfomaların B-hücreli, T-hücreli ve doğal katil/T hücreli olmak üzere üç alt tipi bulunmaktadır.…”