Syncope after Influenza Virus Infection

Noh, Sang Mi; Kang, Hyun Goo; Kim, Bum Joon

doi:10.3346/jkms.2020.35.e134

Cited by 9 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For perspective, it is relevant to note that a prior report on a cohort of 651 patients with influenza, noted the incidence of syncope to be 2.2% (14 patients) 24 . They described a significantly younger population (mean age 48 ± 20 years), but like our report, they did not note any serious arrhythmias.…”

Section: Discussionsupporting

confidence: 64%

Syncope and presyncope in patients with COVID‐19

Oates

Turagam

Musikantow

et al. 2020

Pacing Clinical Electrophis

View full text Add to dashboard Cite

Introduction: Recent studies have described several cardiovascular manifestations of COVID-19 including myocardial ischemia, myocarditis, thromboembolism, and malignant arrhythmias. However, to our knowledge, syncope in COVID-19 patients has not been systematically evaluated. We sought to characterize syncope and/or presyncope in COVID-19. Methods: This is a retrospective analysis of consecutive patients hospitalized with laboratory-confirmed COVID-19 with either syncope or presyncope. This "study" group (n = 37) was compared with an age and gender-matched cohort of patients without syncope ("control") (n = 40). Syncope was attributed to various categories. We compared telemetry data, treatments received, and clinical outcomes between the two groups. Results: Among 1000 COVID-19 patients admitted to the Mount Sinai Hospital, the incidence of syncope/presyncope was 3.7%. The median age of the entire cohort was 69 years (range 26-89+ years) and 55% were men. Major comorbidities included hypertension, diabetes, and coronary artery disease. Syncopal episodes were categorized as (a) unspecified in 59.4% patients, (b) neurocardiogenic in 15.6% patients, (c) hypotensive in 12.5% patients, and (d) cardiopulmonary in 3.1% patients with fall versus syncope and seizure versus syncope in 2 of 32 (6.3%) and 1 of 33 (3.1%) patients, respectively. Compared with the "control" group, there were no significant differences in both admission and peak blood levels of d-dimer, troponin-I, and CRP in the "study" group. Additionally, there were no differences in arrhythmias or death between both groups. Conclusions: Syncope/presyncope in patients hospitalized with COVID-19 is uncommon and is infrequently associated with a cardiac etiology or associated with adverse outcomes compared to those who do not present with these symptoms.

show abstract

Section: Discussionsupporting

confidence: 64%

Syncope and presyncope in patients with COVID‐19

Oates

Turagam

Musikantow

et al. 2020

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

“…The prevalence of presyncope among patients with SARS-CoV-2 was slightly higher than that previously reported for patients after influenza (2.7 vs 2.2%, respectively) [ 34 ], with females typically more affected than males [ 15 ]. The percentage of dizziness attributable to presyncope was not negligible (16.3%).…”

Section: Discussionmentioning

confidence: 60%

“…Most syncopal episodes in COVID-19 patients have been etiologically classified as unspecified, with no increased risk of adverse outcomes [ 35 , 36 ]. SARS-CoV-2 infection might be responsible for presyncope/syncope through several mechanisms, including viral myocarditis, adrenergic denervation, autoimmune autonomic neuropathy, and dehydration due to sweating, vomiting, diarrhea, low water intake or medications (such as angiotensin receptor blocking agents) [ 34 – 36 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of symptoms in 1512 COVID-19 patients: have dizziness and vertigo been underestimated thus far?

et al. 2022

View full text Add to dashboard Cite

The relationship between SARS-CoV-2 infection and dizziness is still unclear. The aim of this study is to assess the prevalence and characteristics of dizziness and vertigo among patients with mild-to-moderate COVID-19. Patients discharged from the emergency rooms with a confirmed SARS-CoV-2 diagnosis were assisted by daily telephone calls until nasopharyngeal swab negativization, and specific symptoms concerning balance disorders were investigated through targeted questions posed by experienced physicians. The study included 1512 subjects (765 females, 747 males), with a median age of 51 ± 18.4 years. New-onset dizziness was reported by 251 (16.6%) patients, among whom 110 (43.8%) complained of lightheadedness, 70 (27.9%) of disequilibrium, 41 (16.3%) of presyncope, and 30 (12%) of vertigo. This study analyzed in detail the prevalence and pathophysiological mechanisms of the different types of balance disorders in a large sample, and the results suggest that dizziness should be included among the main symptoms of COVID-19 because one-sixth of patients reported this symptom, with females being significantly more affected than males (20.3 vs 12.9%, P < 0.001). Most cases of dizziness were attributable to lightheadedness, which was probably exacerbated by psychophysical stress following acute infection and mandatory quarantine. Vertigo should not be underestimated because it might underlie serious vestibular disorders, and disequilibrium in elderly individuals should be monitored due to the possible risk of falls.

show abstract

“…Orthostatic hypotonia and syncope associated with viral diseases may be caused by the loss of gastrointestinal fluid, prolonged bed rest, and the deterioration of cardiovascular and visceral sensory system conditions after acute disease [10].…”

Section: Open Accessmentioning

confidence: 99%

Orthostatic hypotonia as a probably late sequela of SARS-CoV-2 infection in a patient provided with palliative home care: a case report

2022

View full text Add to dashboard Cite

Background The SARS-CoV-2 pandemic has become a challenge for the entire healthcare system. Treatment for COVID-19 includes casual and symptomatic management in the acute phase of the disease and focuses on the treating early complications of the disease. Long-term health consequences of the infection have not yet been fully identified. A special group of patients with comorbidities, including neoplastic disease for whom the interpretation and management of symptoms is a major challenge. Case presentation In this case report, we present a 73-year-old woman with recently diagnosed gastric adenocarcinoma in whom we diagnosed orthostatic hypotonia in the aftermath of SARS-CoV-2 infection. We administered thiethylperazine maleate 6.5 mg daily. Additionally, we advised the patient to slowly lift from the recumbent position, raise the headboard, take meals in small portions, and increase fluid intake. These pharmacological and nonpharmacological measures resulted in sustained relief of dizziness and nausea. Conclusions The occurrence of orthostatic hypotonia seems a possible late sequela of SARS-CoV-2 infection, and simple measures appeared sufficient to achieve sustained symptom control.

show abstract

Syncope after Influenza Virus Infection

Cited by 9 publications

References 8 publications

Syncope and presyncope in patients with COVID‐19

Syncope and presyncope in patients with COVID‐19

Prevalence of symptoms in 1512 COVID-19 patients: have dizziness and vertigo been underestimated thus far?

Orthostatic hypotonia as a probably late sequela of SARS-CoV-2 infection in a patient provided with palliative home care: a case report

Contact Info

Product

Resources

About