Syndromal and Nonsyndromal Cleft Lip with or without Cleft Palate in Kuwait

Facial Clefting in Arab Populations: Analysis of 134 Cases

“…10,12,14,[21][22][23] Broad disagreement is notable in regard to data for the Arab population. 7,12,16,24 Our incidence of 1.54 per 1000 births agrees with Kuwait's incidence of 1.5 24 and 1.48 12 and with the incidence in various European countries. 14,22 However, it is not as low as a Libyan report of 0.52.…”

“…7 Wide variation exists with respect to percentages of various cleft types among reports from Arab countries. 7,12,16,24 Although the sex difference was not statistically significant, males outweighed (in numbers) females in cleft lip (63%) and cleft lip with cleft palate (54%); for cleft palate, males were slightly less affected (47.7%) ( Table 2). This finding tallies with most reports 4,5,12,22 which show more prominent sex difference in various cleft types.…”

“…7,12 However, a very high incidence (56%) was reported in one series from Kuwait. 24 It is possible that the pattern of associated anomalies could be underestimated, since it is usually based on examination of the newborn and additional anomalies are detected with increasing age, 2,25 while other anomalies need special investigation. 26 In this study, only major anomalies were reported.…”

Congenital Malformations in Primary Health Care in Al-Qassim Region

“…With special reference to alimentary tract malformations, we found the similar patterns of cleft lip with or without cleft palate as reported in a study from Kuwait. 9 Despite some caveats already highlighted, we suggest that data of this preliminary research might be utilized as a data base for future analytical research involving several other etiological factors 15,22,25 related to congenital malformations in Saudi Arabia.…”

“…1,2,6,7 Furthermore, some studies have explored the individual specific body system's CMs. [8][9][10][11] The former studies have, however, some limitations as a majority of these are hospital-based, do not reflect the prevalence of CMs in the general population, are carried out in neonates only, and moreover do not provide data regarding other age groups surviving with congenital malformations. Notably, as a result of multiple favorable factors, the perinatal and infant mortality and morbidity rates attributable to major congenital malformations have considerably decreased in the developing world, though not as sharply as in developed countries.…”