Syndrome de Good et toxoplasmose congénitale secondaire à une réactivation maternelle pendant la grossesse

Disseminated and Congenital Toxoplasmosis in a Mother and Child With Activated PI3-Kinase δ Syndrome Type 2 (APDS2): Case Report and a Literature Review of Toxoplasma Infections in Primary Immunodeficiencies

“…Patients with Good Syndrome have thymomas with combined cellular and humoral immunodeficiency and autoimmunity. Cerebral and disseminated Toxoplasma infection was reported in one patient with Good syndrome (39), and Toxoplasma reactivation in pregnancy resulting in congenital toxoplasmosis has been described in another patient with the same disease (40). Further studies are needed to characterize the molecular and cellular mechanisms predisposing to Toxoplasma infection in this patient population.…”