Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Kapoor, Indu; Singh, Gyaninder Pal

doi:10.1016/b978-0-12-804075-1.00030-4

Cited by 1 publication

(2 citation statements)

References 15 publications

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“…Vitamin D [143][144][145][146][147][148][149][150] Calcium * PPIs: proton pump inhibitors are commonly used to reduce the production of stomach acid. ** SSRIs: selective serotonin reuptake inhibitors are commonly used to treat depression and anxiety disorders.…”

Section: Corticosteroidsmentioning

confidence: 99%

“…Therefore, special attention should be paid to the elderly population, as they may be more susceptible to the risk of hyponatremia [147]. The process by which these drugs induce sodium depletion is not fully explained, but in many cases, hyponatremia appears to be a consequence of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) [148]. It is thought that antidepressants may stimulate the release of antidiuretic hormone (ADH), possibly by increased serotonin activity, or they may increase the renal response to ADH.…”

Section: Central Nervous System (Cns) Medications-antidepressantsmentioning

confidence: 99%

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An Update on Drug–Nutrient Interactions and Dental Decay in Older Adults

Bell,

Rodrigues,

Antoniadou

et al. 2023

Nutrients

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In recent decades, the global demographic landscape has undergone a discernible shift that has been characterised by a progressive increase in the proportion of elderly individuals, indicative of an enduring global inclination toward extended lifespans. The aging process, accompanied by physiological changes and dietary patterns, contributes to detrimental deviations in micronutrient consumption. This vulnerable aging population faces heightened risks, including dental caries, due to structural and functional modifications resulting from insufficient nutritional sustenance. Factors such as physiological changes, inadequate nutrition, and the prevalence of multiple chronic pathologies leading to polypharmacy contribute to the challenge of maintaining an optimal nutritional status. This scenario increases the likelihood of drug interactions, both between medications and with nutrients and the microbiome, triggering complications such as dental decay and other pathologies. Since the drug industry is evolving and new types of food, supplements, and nutrients are being designed, there is a need for further research on the mechanisms by which drugs interfere with certain nutrients that affect homeostasis, exemplified by the prevalence of caries in the mouths of older adults. Infectious diseases, among them dental caries, exert serious impacts on the health and overall quality of life of the elderly demographic. This comprehensive review endeavours to elucidate the intricate interplay among drugs, nutrients, the microbiome, and the oral cavity environment, with the overarching objective of mitigating the potential hazards posed to both the general health and dental well-being of older adults. By scrutinising and optimising these multifaceted interactions, this examination aims to proactively minimise the susceptibility of the elderly population to a spectrum of health-related issues and the consequences associated with dental decay.

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