Syndrome Porc/Chat : accident allergique fatal apres ingestion de sanglier

Drouet, M.; Sabbah, A; Hassoun, S; Sellin, J. Le; Bonneau, J. C.; Gay, G.; Dubois, C

doi:10.1016/s0335-7457(01)80059-9

Cited by 3 publications

(3 citation statements)

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“…There is currently insufficient information for any of the different forms of meat allergy to predict with high sensitivity and high specificity the presence and/or severity of reactions to red meat [57]. Similar to other allergic diseases, co-factors such as alcohol, exercise and NSAIDs may play a role in contributing to the severity of clinical reactions to mammalian meat [31,47,58].…”

Section: Diagnosis and Managementmentioning

confidence: 99%

Red meat allergy in children and adults

Wilson

Platts-Mills

2019

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of Review: To highlight recent advances in our understanding of the clinical features, prevalence and pathophysiology of red meat allergy.Recent findings: Allergic reactions to red (ie, mammalian) meat have historically been considered rare and described primarily in young atopic children. It is now clear that red meat allergy is not uncommon in some parts of the world in other age groups. Strikingly, the majority of these cases relate to specific IgE to galactose-α-1,3-galactose (α-Gal), an oligosaccharide of nonprimate mammals. The mechanism of sensitization in this syndrome relates to bites of certain hard ticks and the clinical reactions often have a delay of 3-6 hours. An additional form of red meat allergy relates to inhalant sensitization to mammalian proteins. The best characterized example involves cat-sensitized subjects with specific IgE to cat serum albumin who can react to ingested pork because of cross-sensitization to pork serum albumin.Summary: Red meat allergy is more common than previously appreciated and relates to at least three different forms that are distinguished by mechanisms of sensitization and have characteristic clinical and immunologic features.

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Section: Diagnosis and Managementmentioning

confidence: 99%

Red meat allergy in children and adults

Wilson

Platts-Mills

2019

Current Opinion in Allergy &Amp; Clinical Immunology

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“…5 In pork-cat syndrome the allergen is pork albumin, which can cross-react with cat albumin because of its 82% amino acid sequence homology. 6,7 In addition, specific allergens could be involved in allergies to offal that contrast with a tolerance to meats of similar origin. 8 Mammalian meat allergies can be related to sensitization to the a-gal oligosaccharide epitope, a glycosylation modification in nonprimate mammalian proteins.…”

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confidence: 99%

“…2,3 Association between asthma and 17q12-21 was identified in white subjects of Northern European ancestry 2 and has been established as a risk factor for early pediatric asthma through replication studies in multiple independent cohorts of the same ancestral background, including our own study. [3][4][5][6] A recent study of 17q12-21 variants in white subjects reported the association was significantly stronger in subjects with early tobacco smoke exposure. 4 This study also found that the genetic variations were more strongly associated with early-onset asthma (before age 4 years) than with late-onset asthma (after age 4 years).…”

mentioning

confidence: 99%