Synergic antifungal and antibacterial activity of alcoholic extract of the species Robinia pseudoacacia L. (Fabaceae)

Rosu, A.F.; Bita, A.; Călina, Daniela; Rosu, L; Zlatian, Ovidiu; Calina, V.

doi:10.1136/ejhpharm-2012-000074.344

Cited by 14 publications

(11 citation statements)

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“…In addition, the 70 % ethanol solvent control showed some activity against K. pneumoniae strains, A. baumannii and Candida sp. These results are in accordance with literature data, i.e., a 90 % ethanolic extracts of R. pseudoacacia leaves and barks were shown to be active against E. coli, P. aeruginosa, Proteus vulgaris, Salmonella choleraesuis and C. albicans strains 27. …”

supporting

confidence: 93%

Antimicrobial and antioxidant activity of the vegetative and reproductive organs of Robinia pseudoacacia

Marinaș

Oprea

Geană

et al. 2014

JSCS

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This study was aimed at investigating the antimicrobial and antioxidant activity of ethanol extracts obtained from the leaves, seeds and sheaths of Robinia pseudoacacia. Total phenolic content (TPC, Folin-Ciocalteu method), antioxidant activity (trolox equivalent antioxidant capacity (TEAC) assay) and antimicrobial activity (agar disk diffusion method and broth dilution method) of the vegetative and reproductive organs of R. pseudoacacia were determined. The highest content of polyphenols (expressed as gallic acid equivalents, GAE) was found in the extract of R. pseudoacacia leaves (266.7 μg GAE mL -1 extract) followed by the extract of the seeds (232.2 μg GAE mL -1 extract). HPLC analysis showed the presence of catechin (0.925 μg mL -1 ), rutin (0.831 μg mL -1 ), resveratrol (0.664 μg mL -1 ) and quercetin (0.456 μg mL -1 ) in the leaf extract, and catechin (0.127 μg mL -1 ), epicatechin (0.239 μg mL -1 ) and rutin (0.231 μg mL -1 ) in the seed extract. The results showed that the studied extracts exhibited a selective antimicrobial effect directed against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli) bacterial strains. The combination leaf extract/antibiotic had the highest synergistic effect when compared to combinations with seed and sheath extracts. The same extract with penicillin G, kanamycin and rifampin had highest synergetic effect against methicillinresistant S. aureus strain (MRSA), a strain that has gained great interest of microbiologists within the past decades. The chemical characterization of ethanol extracts from the vegetative and reproductive organs of R. pseudoacacia, the synergistic effects of certain antibiotics and acacia extracts and the potential to increase the antimicrobial activity of some commercial antibiotics against MRSA were investigated for the first time.

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confidence: 93%

Antimicrobial and antioxidant activity of the vegetative and reproductive organs of Robinia pseudoacacia

Marinaș

Oprea

Geană

et al. 2014

JSCS

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“…Further, Gurudeeban et al [ 16 ] reported high antibacterial activity of the methanolic extracts of C. colocynthis fruits against bacteria, such as B. subtilis , Streptococcus pyogenes , and Salmonella typhi . Robinin extracted from Robinia pseudoacacia L. has high antibacterial activity [ 55 , 56 ]. Benzoic acid and its derivatives have antibacterial activities and might be used as food preservatives [ 57 ].…”

Section: Discussionmentioning

confidence: 99%

Bioactivities of Traditional Medicinal Plants in Alexandria

Elansary

Szopa

Kubica

et al. 2018

Evidence-Based Complementary and Alternative Medicine

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In traditional folklore, medicinal herbs play a vital role in the prevention and treatment of microbial diseases. In the present study, the phenolic profiles of the medicinal plants Asparagus aethiopicus L., Citrullus colocynthis L., Senna alexandrina L., Kalanchoe delagoensis L., Gasteria pillansii L., Cymbopogon citratus, Brassica juncea, and Curcuma longa L. were determined by high-performance liquid chromatography with a diode-array detector method. The results revealed rich sources of important compounds such as robinin in the fruits and leaves of A. aethiopicus; caffeic acid in the tubers of A. aethiopicus and quercitrin in the leaves of G. pillansii. Further, relatively high antioxidant, antibacterial, and antifungal activities were observed in C. colocynthis fruit coat, S. alexandrina pods, and A. aethiopicus leaves, respectively. The relatively higher the bioactivities of plants extracts associated with the phenols in these plants, in particular, the more abundant the phenols. Therefore, it was concluded that the fruit coat of C. colocynthis, pods of S. alexandrina, and leaves of A. aethiopicus might be excellent sources of natural products. These plant extracts also have a wide spectrum of antimicrobial activities that could be used in the pharmaceutical industries and to control diseases.

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“…In the case of most microorganisms, it is reported that their growth was inhibited by concentration of 2.00 mg/mL. Rosu et al [34] reported that extracts from different parts of the plant had different antibacterial activities. Extracts of false acacia flowers and seeds were efficient antibacterials for Gram positive cocci.…”

Section: Microbiological Analysesmentioning

confidence: 99%

Chemical composition and application of flowers of false acacia (Robinia pseudoacacia L.)

Stankov¹,

Fidan²,

Ivanova³

et al. 2018

Ukr

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Introduction. The study was carried out to determine the chemical composition and biological activity of false acacia flowers and their products (concrete and syrups) grown in Bulgaria. Materials and methods. Concrete was obtained by extraction with n-hexane and its chemical composition was determined by GC-MS. Syrups with different concentrations have been obtained and their polyphenols content, antimicrobial and antioxidant activity were established. Result and discussion. The yield of concrete was 1.06% and the major constituents of the concrete are as follows: n-nonacosane (25.18%), n-heptacosane (20.10%), α-linolenic acid (5.97%), n-pentacosane (4.98%), palmitic acid (4.92%), diisooctyl phthalate (4.05%), hexahydrofarnesyl acetone (3.86%), linoleic acid (3.64%), isopropyl myristate (3.47%), and n-hentriacontane (3.39%). The total aliphatic hydrocarbons constituted the highest percentage of the component of the concrete constituting 61.50%. The minerals identified as biggest content in the tested samples of false acacia flowers are nickel, copper, calcium and chromium. Higher values of phenolic compounds in the flowers (0.77 mg GAE/mL) than those of the syrup 60 °Brix (0.06 mg GAE/mL) and R. pseudoacacia syrup 70 °Brix (0.14 mg GAE/mL) were found. The syrup samples exhibit antimicrobial properties against foodborne pathogenic bacteria as Salmonella, E. coli and L. monocytogenes. Conclusion. Based on the chemical and biochemical properties of false acacia flowers, it could be recommended as a potential raw material for food, pharmaceutical and cosmetic products.

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Synergic antifungal and antibacterial activity of alcoholic extract of the species Robinia pseudoacacia L. (Fabaceae)

Cited by 14 publications

References 0 publications

Antimicrobial and antioxidant activity of the vegetative and reproductive organs of Robinia pseudoacacia

Antimicrobial and antioxidant activity of the vegetative and reproductive organs of Robinia pseudoacacia

Bioactivities of Traditional Medicinal Plants in Alexandria

Chemical composition and application of flowers of false acacia (Robinia pseudoacacia L.)

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