Synergistic antimicrobial potential of essential oils in combination with nanoparticles: Emerging trends and future perspectives

Rai, Mahendra; Paralikar, Priti; Jogee, Priti; Agarkar, Gauravi; Ingle, Avinash P.; Derita, Marcos Gabriel; Zacchino, Susana

doi:10.1016/j.ijpharm.2017.01.013

Cited by 182 publications

(103 citation statements)

References 131 publications

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“…Inclusion of natural components in nanoparticles fabrication have recently been encouraged to change the carrier matrix and boost the antibiotics efficacy [186].…”

Section: Combination Of Nanotechnology and Natural Compoundsmentioning

confidence: 99%

Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations

et al. 2020

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Based on the recent reports of World Health Organization, increased antibiotic resistance prevalence among bacteria represents the greatest challenge to human health. In addition, the poor solubility, stability, and side effects that lead to inefficiency of the current antibacterial therapy prompted the researchers to explore new innovative strategies to overcome such resilient microbes. Hence, novel antibiotic delivery systems are in high demand. Nanotechnology has attracted considerable interest due to their favored physicochemical properties, drug targeting efficiency, enhanced uptake, and biodistribution. The present review focuses on the recent applications of organic (liposomes, lipid-based nanoparticles, polymeric micelles, and polymeric nanoparticles), and inorganic (silver, silica, magnetic, zinc oxide (ZnO), cobalt, selenium, and cadmium) nanosystems in the domain of antibacterial delivery. We provide a concise description of the characteristics of each system that render it suitable as an antibacterial delivery agent. We also highlight the recent promising innovations used to overcome antibacterial resistance, including the use of lipid polymer nanoparticles, nonlamellar liquid crystalline nanoparticles, anti-microbial oligonucleotides, smart responsive materials, cationic peptides, and natural compounds. We further discuss the applications of antimicrobial photodynamic therapy, combination drug therapy, nano antibiotic strategy, and phage therapy, and their impact on evading antibacterial resistance. Finally, we report on the formulations that made their way towards clinical application.

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“…Inclusion of natural components in nanoparticles fabrication have recently been encouraged to change the carrier matrix and boost the antibiotics efficacy [186].…”

Section: Combination Of Nanotechnology and Natural Compoundsmentioning

confidence: 99%

Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations

et al. 2020

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“…Formulation technologies for overcoming these drawbacks include nanoemulsions, β‐cyclodextrin encapsulation, and various polymer‐based films . Recently, novel encapsulation technologies enabling sustained release have become an important strategy for improving the applicability of natural antimicrobials, and encapsulation into nanocomposites has proved suitable for protecting and preserving the effectiveness of bioactive substances . However, the porous structures used for encapsulation are typically produced via expensive and complex synthetic routes.…”

Section: Introductionmentioning

confidence: 99%

“…18 Recently, novel encapsulation technologies enabling sustained release have become an important strategy for improving the applicability of natural antimicrobials, and encapsulation into nanocomposites has proved suitable for protecting and preserving the effectiveness of bioactive substances. [19][20][21][22][23][24] However, the porous structures used for encapsulation are typically produced via expensive and complex synthetic routes. Natural nanoclays, which are costefficient and widely used in nanomaterial applications, represent a potentially suitable alternative support for storage and release applications.…”

Section: Introductionmentioning

confidence: 99%

The efficacy of essential oil components loaded into montmorillonite against Aspergillus niger and Staphylococcus aureus

Bernardos

Božík

Álvarez

et al. 2019

Flavour & Fragrance J

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Essential oil components (EOCs) are potent natural antimicrobial agents, but their high volatility and reactivity limit their potential applications. Here, we report the preparation of a series of nanomaterials containing EOCs (i.e., allyl isothiocyanate, carvacrol, cinnamaldehyde, diallyl disulphide, eugenol and thymol). The materials were prepared by simple adsorption of the EOCs onto a montmorillonite nanoclay. The antimicrobial activities of these materials were assessed against Aspergillus niger and Staphylococcus aureus as typical models of agricultural fungal pathogens and foodborne bacterial pathogens, respectively. In addition, the activities of the encapsulated EOCs were compared with those of the corresponding free forms with or without Tween‐80 in two types of assays: microdilution assays for determining the minimum inhibitory concentration (MIC) and agar‐based assays mimicking surface treatment. Enhanced antifungal activity of the encapsulated form was observed for all EOCs. In addition, against S. aureus, the MICs of all EOCs were remarkably lower in encapsulated form than in free form. These results indicate that EOCs encapsulated in low‐cost nanoclays have favourable potential as antimicrobials compared with the pure compounds.

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“…Recently, Rai et al . () discussed the emerging trends and future prospects of the synergistic antimicrobial potential of essential oils in combination with nanoparticles. These authors described that the encapsulation of essential oils in nanoparticles is a promising strategy as these systems can facilitate the application of these compounds as antimicrobial agents.…”

Section: Future Trendsmentioning

confidence: 99%

“…Many of these studies can contribute to solving real problems in aquaculture, as they evaluate the bactericidal and antifungal efficacy and, in this context, could be used to treat fish diseases. Recently, Rai et al (2017) discussed the emerging trends and future prospects of the synergistic antimicrobial potential of essential oils in combination with nanoparticles. These authors described that the encapsulation of essential oils in nanoparticles is a promising strategy as these systems can facilitate the application of these compounds as antimicrobial agents.…”

Section: Future Trendsmentioning

confidence: 99%

Trends in aquaculture sciences: from now to use of nanotechnology for disease control

Luis

Campos

Oliveira

et al. 2017

Reviews in Aquaculture

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Aquaculture is increasingly important in global food production. Consequently, the control of diseases in aquaculture is essential, due to the potential environmental impacts, notably in terms of the states of health of freshwater bodies and the oceans. In this study, we review the possible uses of different management systems, highlighting essential oils and novel nanotechnological strategies, for the control of diseases in aquaculture.

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Synergistic antimicrobial potential of essential oils in combination with nanoparticles: Emerging trends and future perspectives

Cited by 182 publications

References 131 publications

Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations

Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations

The efficacy of essential oil components loaded into montmorillonite against Aspergillus niger and Staphylococcus aureus

Trends in aquaculture sciences: from now to use of nanotechnology for disease control

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