2024
DOI: 10.1155/2024/1083143
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Synergistic Effects of Icariin and Extracellular Vesicles Derived from Rabbit Synovial Membrane‐Derived Mesenchymal Stem Cells on Osteochondral Repair via the Wnt/β‐Catenin Pathway

Dongming Tang,
Wang Tang,
Huanqing Chen
et al.

Abstract: Objectives. Osteochondral defects (OCDs) are localized areas of damaged cartilage and underlying subchondral bone that can produce pain and seriously impair joint function. Literature reports indicated that icariin (ICA) has the effect of promoting cartilage repair. However, its mechanism remains unclear. Here, we explored the effects of icariin and extracellular vesicles (EVs) from rabbit synovial‐derived mesenchymal stem cells (rSMSCs) on repairing of OCDs. Materials and Methods. Rabbit primary genicular cho… Show more

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