Synergistic Enhancement of Antibacterial and Osteo‐Immunomodulatory Activities of Titanium Implants via Dual‐Responsive Multifunctional Surfaces
Qing Wang,
Ya Gao,
Yanzheng Chen
et al.
Abstract:Bone implant‐associated infections and inflammations, primarily caused by bacteria colonization, frequently result in unsuccessful procedures and pose significant health risks to patients. To mitigate these challenges, the development of engineered implants with spatiotemporal regulation capabilities, designed to inhibit bacterial survival and modulate immune responses in the early stage, while promoting bone defect healing in the late stage is proposed. The implants are functionalized with ε‐poly‐l‐lysine‐phe… Show more
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