Synergistic inhibition of catalase activity by food colorants sunset yellow and curcumin: An experimental and MLSD simulation approach

Khataee, Simin; Dehghan, Gholamreza; Rashtbari, Samaneh; Yekta, Reza

doi:10.1016/j.cbi.2019.108746

Cited by 12 publications

(7 citation statements)

References 45 publications

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“…The successful covalent conjugation between TCPP and CAT could be proven by the Fourier transform infrared (FTIR) spectra (Figure S1, Supporting Information). [ 14 ] From the UV–visible absorbance spectra of Figure 1b, we found that the characteristic absorption peaks at 414 nm of TCPP could be observed after the conjugation with CAT. As verified in our previous researches, [ 4d,15 ] CAT could decompose H 2 O 2 into O 2 quickly.…”

Section: Resultsmentioning

confidence: 99%

Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection

She

Zhou

Zhang

et al. 2020

Adv Healthcare Materials

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Sonodynamic therapy (SDT) by utilizing ultrasonic waves triggers the generation of reactive oxygen species (ROS) with the help of sonosensitizers to destruct deep‐seated tumors has attracted great attention. However, the efficacy of SDT may not be robust enough due to the insufficient oxygen supply within solid tumors. Additionally, repeated injections and treatments, which are often required to achieve the optimal therapeutic responses, may cause additional side effects and patient incompliance. Herein, a thermo‐triggered in situ hydrogel system is developed in which catalase (CAT) conjugated with sonosensitizer meso‐tetra (4‐carboxyphenyl) porphine (TCPP) is mixed into chitosan (CS) and beta‐glycerol phosphate disodium (GP) to form the precursor solution. After injection of the precursor solution into tumors, the in situ sol–gel transformation will occur as triggered by the body temperature, resulting in the localized tumor retention of TCPP‐CAT. The locally restrained TCPP‐CAT not only produces ROS under ultrasonic treatment, but also sustainably reverses the oxygen‐deficient status in solid tumors by triggering the O2 generation from the decomposition of endogenous H2O2, further promoting the efficacy of SDT. As a result, the repeated SDT after a single dose injection of such a hydrogel can offer robust treatment effects to effectively eradicate tumors.

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Section: Resultsmentioning

confidence: 99%

Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection

She

Zhou

Zhang

et al. 2020

Adv Healthcare Materials

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“… Mofidi Najjar et al (2017) showed that various concentrations of curcumin could increase the amount of α-helix content of catalase, which played an important role in the enhancement of the enzyme activity of catalase. Afterward, they also found that curcumin supplement resulted in the decreases in accessible surface area (ASA) and pKa of catalase, leading to the enhancement of the enzyme activity of bovine liver catalase (BLC) ( Khataee et al, 2019 ). Therefore, curcumin can enhance the enzyme activities of various types of antioxidase, mitigating the excessive oxidative stress during reperfusion phase.…”

Section: Curcumin Suppresses the Excessive Oxidative Stressmentioning

confidence: 99%

Role of curcumin in ischemia and reperfusion injury

Zhang

2023

Front. Pharmacol.

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Ischemia-reperfusion injury (IRI) is an inevitable pathological process after organic transplantations. Although traditional treatments restore the blood supply of ischemic organs, the damage caused by IRI is always ignored. Therefore, the ideal and effective therapeutic strategy to mitigate IRI is warrented. Curcumin is a type of polyphenols, processing such properties as anti-oxidative stress, anti-inflammation and anti-apoptosis. However, although many researches have been confirmed that curcumin can exert great effects on the mitigation of IRI, there are still some controversies about its underlying mechanisms among these researches. Thus, this review is to summarize the protective role of curcumin against IRI as well as the controversies of current researches, so as to clarify its underlying mechanisms clearly and provide clinicians a novel idea of the therapy for IRI.

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“…Eight studies used molecular docking to understand the toxicity of artificial azo dyes. Inhibition of pepsin (Mohseni‐Shahri et al., 2018) and catalase (Khataee et al., 2019) activity in a noncompetitive manner has been demonstrated for Sunset Yellow FCF. When used in conjunction with the natural dye curcumin, the synergistic effect increases the stability of the Sunset Yellow FCF–catalase complex and the inhibition of enzyme activity (Khataee et al., 2019).…”

Section: Risk Assessment Of Artificial Azo Dyesmentioning

confidence: 99%

“…Inhibition of pepsin (Mohseni‐Shahri et al., 2018) and catalase (Khataee et al., 2019) activity in a noncompetitive manner has been demonstrated for Sunset Yellow FCF. When used in conjunction with the natural dye curcumin, the synergistic effect increases the stability of the Sunset Yellow FCF–catalase complex and the inhibition of enzyme activity (Khataee et al., 2019). In contrast, the van der Waals and hydrogen bonds of Allura Red AC form a stable complex with pepsin, which increases the enzyme activity (Balaei et al., 2021).…”

Section: Risk Assessment Of Artificial Azo Dyesmentioning

confidence: 99%

“…The possibility of tracking probable interactions and determining which food components will have a greater affinity for synergistic or antagonistic actions is an important ally to guide the risk assessment of azo dyes. This type of approach is used with human serum albumin and azo dyes for toxicological effect studies (Masone et al., 2015; Khataee et al., 2019; Balaei et al., 2021).…”

Section: Future Perspectives On the Use Of Azo Dyes In Foodmentioning

confidence: 99%

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Risk assessment of azo dyes as food additives: Revision and discussion of data gaps toward their improvement

Ramos-Souza

Bandoni

Arisseto-Bragotto

et al. 2022

Comp Rev Food Sci Food Safe

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The food industry uses dyes mainly to overcome color loss during the processing and storage of products, with the azo dyes currently being the most employed. Studies on the safety of using these dyes in foods started in the 1950s and have indicated the potential for concern. This review discusses the risk assessment of food intake containing artificial azo dyes. There are case reports and, subsequently, double‐blind placebo‐controlled trials in some individuals who may experience adverse effects from the intake of azo dyes, but it is unclear whether these adverse effects are restricted to specific populations or more generalized. In view of this, different toxicological endpoints are evaluated to verify toxic effects in in vitro and in vivo models and to establish the no observed adverse effect level. Exposure estimation studies have shown that human exposure to azo dyes via oral intake is mainly below the acceptable daily intake established by advisory bodies. However, most countries do not have studies that estimate the oral intake of azo dyes. In this case, local food diversity and racial–ethnic specificities are not considered when stating the exposure estimate is below the acceptable daily intake for the human population and thus may not represent actual intake. Concerning the scenario established above, this review discusses the most critical gaps to be overcome to contribute to the direction of future studies and the development of more effective public policies concerning the safety of the intake of artificial azo dyes.

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Synergistic inhibition of catalase activity by food colorants sunset yellow and curcumin: An experimental and MLSD simulation approach

Cited by 12 publications

References 45 publications

Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection

Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection

Role of curcumin in ischemia and reperfusion injury

Risk assessment of azo dyes as food additives: Revision and discussion of data gaps toward their improvement

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