After more than three years, we start to see the end of the tunnel of the COVID-19 pandemic and are ready for reopening (Abbass et al., 2022;Suh and Alhaery, 2022;Kumar et al., 2021).Here, the guest editors and co-editors would like to wish all of our readers and authors good health and let us walk through the pandemic together. We continue to present part 3 of our special issue on the COVID-19 Pandemic and Health Informatics in this issue. In the past two parts (Huang et al., 2021(Huang et al., , 2022, we presented 28 papers; in this issue, we present the following 14 papers on three aspects of research.