Synergistic recognition and electrochemical sensing of 17β-Estradiol using ordered molecularly imprinted polymer-graphene oxide-silver nanoparticles composite films

Regasa, Melkamu Biyana; Nyokong, Tebello

doi:10.1016/j.jelechem.2022.116713

Cited by 11 publications

(11 citation statements)

References 42 publications

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“…Aggravation or enhancement of the electron transfer pathway of AgNPs-modified WE leads to the amplification or decrement of voltammetric performance. Two voltammetric platforms based on MIPs supported by AgNPs-decorated GCE have been developed for highly selective and sensitive detection of natural estrogen in environmental and drinking water with picomolar and femtomolar detection limits [ 182 , 183 ]. The detection of the analyte is catalyzed by the AgNPs (signal amplification or inhibition), while the analyte capture and selective recognition were performed by the MIPs.…”

Section: Discussionmentioning

confidence: 99%

“…In the presence of E2, more imprinted cavities of the poly( p -aminophenol) (MIP-pAPh) were occupied, resulting in direct amplification of the current response by AgNPs signal amplification [ 182 ]. The reverse sensing mechanism was proposed for the AgNP/GO/MIP (poly-imidazole; PImi) functional platform [ 183 ]. In addition to the imidazole moiety ( p -type-electron acceptor), additional functional sites of GO ( n -type electron donor) were available for analyte binding, which blocked the diffusion of the ferri/ferrocyanide redox probe at the electrode/solution interface, reducing the SWV current responses.…”

Section: Discussionmentioning

confidence: 99%

“…Since the size, shape, and orientation of the recognition sites of the cavities imprinted in MIP directly reflect the properties of the analyte, the molecular imprint technology is more than efficient for the development of highly selective sensors. MIPs in combination with AgNPs and AgNPs/GO composites have proven to be exquisite sensing platforms—picomolar and femtomolar LOD values have been achieved for the detection of the endocrine-disrupting 17-β-estradiol in real water matrices [ 182 , 183 ].…”

Section: Discussionmentioning

confidence: 99%

“…SWV measurements ( n = 3) showed that the 17β-estradiol MIP sensor responded to the increasing E2 concentrations from 10 pM to 100 nM, and had a LOD value of 1.86 pM. An electrochemical MIPs-nanocomposite sensor, this time made of ternary poly-imidazole (PImi)-graphene oxide (GO)-AgNPs hybrid material for the selective detection of E2 in river water, was fabricated by the same authors as in the previously published work [ 183 ]. The nanosilver material serves as a catalyst and charge carrier, imidazole-based MIP ( p -type-electron acceptor) provides specific binding cavities for the analyte, and the role of GO ( n -type-electron donor) in the composite material is to provide additional functional units to bind the template.…”

Section: Application Of Silver Nanoparticles In Voltammetric and Ampe...mentioning

confidence: 99%

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The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Ivanišević

2023

Sensors

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With rapidly increasing environmental pollution, there is an urgent need for the development of fast, low-cost, and effective sensing devices for the detection of various organic and inorganic substances. Silver nanoparticles (AgNPs) are well known for their superior optoelectronic and physicochemical properties, and have, therefore, attracted a great deal of interest in the sensor arena. The introduction of AgNPs onto the surface of two-dimensional (2D) structures, incorporation into conductive polymers, or within three-dimensional (3D) nanohybrid architectures is a common strategy to fabricate novel platforms with improved chemical and physical properties for analyte sensing. In the first section of this review, the main wet chemical reduction approaches for the successful synthesis of functional AgNPs for electrochemical sensing applications are discussed. Then, a brief section on the sensing principles of voltammetric and amperometric sensors is given. The current utilization of silver nanoparticles and silver-based composite nanomaterials for the fabrication of voltammetric and amperometric sensors as novel platforms for the detection of environmental pollutants in water matrices is summarized. Finally, the current challenges and future directions for the nanosilver-based electrochemical sensing of environmental pollutants are outlined.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Application Of Silver Nanoparticles In Voltammetric and Ampe...mentioning

confidence: 99%

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The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Ivanišević

2023

Sensors

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“…Emerging environmental pollutants include natural and synthetic estrogens that are discharged into the environment by wastewater treatment plants, pharmaceutical companies, and cattle farms. 17β‐Estradiol (E2), one of the natural estrogens, is the primary bioactive compound discharged into the environment via urine, medicinal product release, during the manufacturing of animal feed for meat‐producing animals, and other agricultural practices that use this chemical (Regasa & Nyokong, 2022b). The most physiologically active estrogen in the body is E2, one of the sex hormones (Wen et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Development of a molecularly imprinted polymer on silanized graphene oxide for the detection of 17‐estradiol in wastewater

Mughal,

Aylaz,

Shaikh

et al. 2024

Water Environment Research

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This research article demonstrates the synthesis, characterization, and electrochemical evaluation of a molecularly imprinted polymer (MIP) on the surface of silanized graphene oxide (silanized GO), which is nanostructured and used to quantify 17‐estradiol (E2) in wastewater. As characterization methods, X‐ray diffraction (XRD), Raman spectroscopy, dynamic scattering light (DSL), scanning electron microscope (SEM), and Fourier transform infrared spectroscopy (FTIR) were utilized to examine the synthesized GO, silanized GO, MIP‐GO composite, and non‐imprinted polymer (NIP)–GO (NIP‐GO) composite. FTIR results confirmed the successful synthesis of GO composites. Raman study confirmed the synthesis of monolayer silanized GO, MIP‐GO composite, and NIP‐GO composite. Surface morphology revealed that after polymerization, the surface of silanized GO sheet‐like morphology is covered with nanoparticles. Adsorption kinetics studies revealed that adsorption follows the pseudo‐second‐order kinetics. Further, we studied the performance of a MIP‐GO‐based sensor by optimizing the effects of pH, scan rate, and incubation period. The linear calibration was achieved between the oxidation peak current and E2 concentration from 0.1 to 0.81 ppm, with a detection limit of 0.037 ppm. The selectivity of the MIP‐GO composite was also checked by using other estrogens, and it was found that E2 is 3.3, 0.5, and 1.4 times more selective than equilin, estriol, and estrone, respectively. The composite was successfully applied to the wastewater samples for the detection of E2, and a good percentage of recoveries were achieved. It suggests that the reported composite can be applied to real samples.Practitioner Points An innovative electrochemical sensor was developed for selective detection of 17‐estradiol through molecularly imprinted polymer fabricated on the surface of silanized GO (MIP‐GO composite). The developed method was comprehensively validated and found to be linear in the range of 0.1 to 0.8 ppm of 17‐estradiol, with 0.037 ppm of limit of detection and 0.1 ppm of limit of quantification, respectively. The developed MIP‐GO‐composite‐based electrochemical sensor was found 3.3, 0.5, and 1.4 times more selective for 17‐estradiol than equiline, estriol, and estrone, respectively. The applicability of a developed sensor was also checked on wastewater samples, and a good percent recovery was obtained.

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Molecularly Imprinted Polymers as Highly Selective Sorbents in Sample Preparation Techniques for Extracting Emerging Pollutants from Environmental Water

Zain,

Hashim,

Yahaya

et al. 2024

Molecularly Imprinted Polymers as Artificial Antibodies for the Environmental Health

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Synergistic recognition and electrochemical sensing of 17β-Estradiol using ordered molecularly imprinted polymer-graphene oxide-silver nanoparticles composite films

Cited by 11 publications

References 42 publications

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Development of a molecularly imprinted polymer on silanized graphene oxide for the detection of 17‐estradiol in wastewater

Molecularly Imprinted Polymers as Highly Selective Sorbents in Sample Preparation Techniques for Extracting Emerging Pollutants from Environmental Water

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