Synovial sarcoma of the head &amp; neck: A review of reported cases in the literature

Stanbouly, Dani; Litman, Eric; Lee, Kevin C.; Philipone, Elizabeth

doi:10.1016/j.jormas.2020.12.001

Cited by 11 publications

(7 citation statements)

References 104 publications

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“…Chemotherapy as adjuvant or neoadjuvant treatment remains controversial [ 8 ], being performed in patients with high risk of metastatic disease [ 6 ]. Adjuvant radiotherapy can be applied in the presence of risk factors, especially for tumors over 5 cm in diameter [ 11 , 15 ]. SS, although characterized by its slow development, has poor prognosis due to local recurrences and distant metastases, particularly in the lungs [ 8 , 16 ].…”

Section: ⧉ Discussionmentioning

confidence: 99%

Neck synovial sarcoma: case presentation

Sapalidis

Laskou²,

Manaki³

et al. 2022

Rom J Morphol Embryol

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Head and neck synovial sarcoma (HNSS) is a rare tumor with a few case reports or case series being published in the literature. We present the case of a 68-year-old patient admitted to our department for management of a palpable neck mass. After initial investigation and due to major problems of differential diagnosis, there was performed a wide excision of the tumor. Histopathology examination revealed an HNSS.

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Section: ⧉ Discussionmentioning

confidence: 99%

Neck synovial sarcoma: case presentation

Sapalidis

Laskou²,

Manaki³

et al. 2022

Rom J Morphol Embryol

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“…However, some studies have recommended using adjuvant radiotherapy in certain unfavorable pathological features, these include positive margins and larger tumor size as in our case [ 13 ]. Although some previous studies have argued the use of chemotherapeutic agents such as doxorubicin for soft tissue sarcomas, we found no solid evidence to support this claim and therefore it was no included in our treatment plan [ 4 , 12 ]. For SS in general, in a national based study from the US, adjuvant chemotherapy with or without radiotherapy was not associated with overall survival in univariate analysis, yet in stage 3 patients both univariate and multivariate analysis showed significant prolongation of overall survival with adjuvant chemotherapy [ 14 ].…”

Section: Discussionmentioning

confidence: 80%

“…This can be challenging to achieve in the complex anatomy of the head and neck region. Inadequate transoral wide local excision is followed by high recurrence rates [ 4 ]. In this advanced case and after reviewing the images with our radiology colleagues in our multidisciplinary team meeting, we elected to employ an open surgical approach to improve the chance of achieving clear surgical margins.…”

Section: Discussionmentioning

confidence: 99%

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Transcervical Approach to Oropharyngeal Synovial Sarcoma: a Case Report

et al. 2022

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Aim: Synovial sarcomas (SS) are malignant tumors rarely arising in the head and neck region. In most of these cases, the tumor arises in the cervical or hypopharyngeal region, and extremely rarely in the oropharynx. Case report: Herein, we report the case of a 22-year-old male oropharyngeal SS patient presented with breathing difficulty and dysphagia. The management plan included an emergency tracheostomy, followed shortly by transcervical resection of the oropharyngeal sarcoma tumor, the pectoralis major myocutaneous flap was used for pharyngeal reconstruction, followed by adjuvant radiotherapy resulting in more than 5 years disease-free survival. Conclusion: SS arising in the oropharynx are extremely rare. Transcervical resection coupled with adjuvant radiotherapy warrants enhanced locoregional control in advanced oropharyngeal cases.

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“…A recent review conducted by the neck (43 cases, representing 17.7%) followed by oral lesion (28 cases, representing 11.5%) 11 .…”

Section: Introductionmentioning

confidence: 99%

Primary soft palate biphasic synovial sarcoma - case report and literature review

Tanase

Neagu

Dascalescu

2021

Romanian Journal of Rhinology

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BACKGROUND. Synovial sarcomas of the soft tissue are a particular type of sarcomas that rarely appear in the head and neck region. CASE REPORT AND COMMENTS. We present the case of a 27-year-old patient diagnosed in 2017 with soft palate biphasic synovial sarcoma who presented with recurrent microepistaxis, nasal obstruction, left cephalalgia and aural fullness in the left ear. The clinical examination showed a tumor with approximately 4/6 cm in diameter, covered with sero-sanguinolent secretions, pulsating in nature, completely obstructing the left choana. The surgical treatment consisted of complete removal of the tumor under endoscopic guidance with electrocauterization of the insertion area, without further postoperative radiotherapy. The histopathological aspect was suggestive for pleomorphic sarcoma, poorly differentiated, confirming the local recurrence of the tumor. The patient also presented lung metastasis from undifferentiated malignant tumor. CONCLUSION. The particularity of this case is represented by the extremely rare occurrence of synovial sarcoma in the head and neck region, especially at the level of the soft palate. Complete resection of the tumor with negative margins represent the mainstay of treatment, associated with adjuvant radiotherapy, with an important role in improving disease-specific survival.

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Synovial sarcoma of the head & neck: A review of reported cases in the literature

Cited by 11 publications

References 104 publications

Neck synovial sarcoma: case presentation

Neck synovial sarcoma: case presentation

Transcervical Approach to Oropharyngeal Synovial Sarcoma: a Case Report

Primary soft palate biphasic synovial sarcoma - case report and literature review

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