SYNTAX score effect on electroencephalography power dynamics in patients undergoing on-pump coronary artery bypass grafting

Abstract

BackgroundThe severity of angiographically assessed coronary artery disease may be the factor that influences the degree of brain damage during on-pump surgery. Modern technology such as computed electroencephalography (EEG) that is used to detect signs of brain damage could also be used to determine the advantages and disadvantages of various surgical myocardial revascularization methods in certain categories of patients. The present study investigated EEG power dynamics for 1 postoperative month in patients undergoing on-pump coronary artery bypass grafting (CABG) who were divided into two groups: those with moderate coronary lesions (SYNTAX score ≤ 22, n = 12) and those with severe coronary lesions (SYNTAX score ≥ 23, n = 18).ResultsAt 7–10 days after CABG, all patients showed theta type 1 rhythm power higher than that seen preoperatively, possibly indicating that brain damage occurred during bypass. At 1 month after CABG, the theta type 1 rhythm power had decreased to the baseline level in patients with SYNTAX scores of ≤22, whereas it had increased in patients with SYNTAX scores ≥23.ConclusionsSYNTAX scores ≥ 23 are associated with EEG markers of perioperative brain damage during CABG. Careful preoperative assessment, preparation, and more effective intraoperative brain protection are essential for this category of coronary heart disease (CHD) patients.

EEG and Clinical Factors Associated with Mild Cognitive Impairment in Coronary Artery Disease Patients

“…In particular, it was shown that the severity of the lesions of the coronary arteries is directly correlated with extracranial and cerebral vascular lesions [33]. In our previous study, we had proposed that the SYNTAX Score might be an indirect indicator of the lesioning of other vascular zones, particularly cerebral arteries [34]. In this study, we found that a greater severity of coronary lesions according to the SYNTAX Score was associated with a high probability of MCI.…”

Beneficial Effects of a Short Course of Physical Prehabilitation on Neurophysiological Functioning and Neurovascular Biomarkers in Patients Undergoing Coronary Artery Bypass Grafting

“…It was suggested that the increased activation of local neural networks is evidence of the involvement of compensatory brain resources. We showed that patients with preoperative PhT at 7-10 days after CABG had a lower increase in slow-wave theta activity associated with perioperative ischemic brain damage (Tarasova et al, 2013). The increase of EEG theta power has been associated with mild cognitive impairment and dementia in relation to disease progression (Babiloni et al, 2021).…”

“…We also established that the integral indicator of attention and overall cognitive status improved after a short course of preoperative training. According to EEG data, patients undergoing physical prehabilitation show a less pronounced postoperative increase in slow-wave theta activity, which may indicate a lower degree of intraoperative brain injury (Tarasova et al, 2013).…”