Synthese Du Metabolite De l'Insecticide Deltamethrine: Alcool Hydroxy‐5 Phenoxy‐3 Benzylique Et De Son Derive Methoxy‐5 Deuteries Et Trities

Abstract

L a b o r a t o i r e d e Chimie e t Biochimie P h a r m c o l o g i q u e s e t Toxicologiques -Unit6 Associee au CNRS en D6veloppement Concert6 avec 1'INSEW (UA-400), 65 rue d e s S a i n t s -P e r e s , 75270 PARIS Cedex 06, France. SUMMARY P a r t i a l h y d r o l y s i s of LiBH4 w i t h d e u t e r a t e d , t r i t i a t e d water i n THF s o l u t i o n provided a simple and cheap method for the p r e p a r a t i o n of d e u t e r a t e d , t r i t i a t e d a l c o h o l s by r e d u c t i o n of esters : (a-2H) a l c o h o l , 5-hydroxy 3-phenoxybenzyl a l c o h o l ( m e t a b o l i t e of d e l t a m e t h r i n , t h e p y r e t h r o i d i n s e c t i c i d e ) . and (a- 5-methoxy-3-phenoxybenzylKey Words : Deuterium, T r i t i u m , P y r e t h r o i d . D e l t a m e t h r i n , Phenoxybenzyl alcohol.