Syntheses and characterization of water‐soluble C<sub>60</sub>–curdlan sulfates for biological applications

Ungurenasu, Cezar; Pinteala, Mariana

doi:10.1002/pola.22010

Cited by 10 publications

(12 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast, side-chain polymers, sometime called onchain or "charm-bracelet," represent the most studied family of polyfullerenes and show the C 60 pending from the main polymer chain. A century of studies on polymers has been exploited in the binding of C 60 to all the "classic" families of polymers such as polystyrenes [79,80], polyacrylates [81,82], polyethers [83], polycarbonates [84], polysiloxanes [85], and polysaccharides [86] in the search for improved processability and enhanced properties, with a wide range of potential applications. In this family can also be included the "double-cable" polymers [87,88], in which the π-conjugated semiconducting polymer (p-type cable) with electron-donating characteristics contains electron-accepting fullerene units covalently connected (n-type cable), with remarkable advantages for construction of photovoltaic devices.…”

Section: Classification and Synthetic Strategiesmentioning

confidence: 99%

Buckyballs

Delgado

Filippone

Giacalone

et al. 2013

Topics in Current Chemistry

View full text Add to dashboard Cite

Buckyballs represent a new and fascinating molecular allotropic form of carbon that has received a lot of attention by the chemical community during the last two decades. The unabating interest on this singular family of highly strained carbon spheres has allowed the establishing of the fundamental chemical reactivity of these carbon cages and, therefore, a huge variety of fullerene derivatives involving [60] and [70]fullerenes, higher fullerenes, and endohedral fullerenes have been prepared. Much less is known, however, of the chemistry of the uncommon non-IPR fullerenes which currently represent a scientific curiosity and which could pave the way to a range of new fullerenes. In this review on buckyballs we have mainly focused on the most recent and novel covalent chemistry of fullerenes involving metal catalysis and asymmetric synthesis, as well as on some of the most significant advances in supramolecular chemistry, namely H-bonded fullerene assemblies and the search for efficient concave receptors for the convex surface of fullerenes. Furthermore, we have also described the recent advances in the macromolecular chemistry of fullerenes, that is, those polymer molecules endowed with fullerenes which have been classified according to their chemical structures. This review is completed with the study of endohedral fullerenes, a new family of fullerenes in which the carbon cage of the fullerene contains a metal, molecule, or metal complex in the inner cavity. The presence of these species affords new fullerenes with completely different properties and chemical reactivity, thus opening a new avenue in which a more precise control of the photophysical and redox properties of fullerenes is possible. The use of fullerenes for organic electronics, namely in photovoltaic applications and molecular wires, complements the study and highlights the interest in these carbon allotropes for realistic practical applications. We have pointed out the so-called non-IPR fullerenes - those that do not follow the isolated pentagon rule - as the most intriguing class of fullerenes which, up to now, have only shown the tip of the huge iceberg behind the examples reported in the literature. The number of possible non-IPR carbon cages is almost infinite and the near future will show us whether they will become a reality.

show abstract

Section: Classification and Synthetic Strategiesmentioning

confidence: 99%

Buckyballs

Delgado

Filippone

Giacalone

et al. 2013

Topics in Current Chemistry

View full text Add to dashboard Cite

show abstract

“…A red shift can be observed in the pyrene fluorescence spectra, and changes in relative peak intensities can be also detected. [13,14] In this passage, the definition of CMC was the ratio of the first vibration peak(I 1 ) and the third vibration peak (I 3 ) based on the analysis of pyrene emission spectra. [36][37][38][39] Figure 10 showed the variation of the intensity ratio (I 1 /I 3 ) vs. solution concentration for amphiphilic graft copolymers PEO-g-PCL.…”

Section: Measurement Of Critical Micelle Concentrationmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] PEO is widely used not only for its hydrophilicity and biocompatibility, but also for some properties of POE present in the materials modified by POE. [6] Among the investigated amphiphilic block copolymers, the biodegradable copolymers are of special interest.…”

Section: Introductionmentioning

confidence: 99%

“…[6] Among the investigated amphiphilic block copolymers, the biodegradable copolymers are of special interest. The biodegradable polymers, such as poly (ε-caprolactone) (PCL) [12][13][14][15][16][17][18] have been used as important biomaterials for a wide variety of drug delivery carriers because of their biocompatibility and biodegradability. The biodegradable polymers PCL modified by PEO have attracted more attention in order to meet the increasing demands for better performances and some specific applications.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis and characterization of a novel amphiphilic poly (ethylene glycol)–poly (ε-caprolactone) graft copolymers

Zhang

Tong

Wu³

et al. 2016

Designed Monomers and Polymers

View full text Add to dashboard Cite

A series of amphiphilic graft copolymers PEO-g-PCL with different poly (ε-caprolactone) (PCL) molecular weight were successfully synthesized by a combination of anionic ring-opening polymerization (AROP) and coordination-insertion ring-opening polymerization. The linear PEO was produced by AROP of ethylene oxide (EO) and ethoxyethyl glycidyl ether initiated by 2-(2-methoxyethoxy) ethoxide potassium, and the hydroxyl groups on the backbone were deprotected after hydrolysis. The ring-opening polymerization of CL was initiated using the linear poly (ethylene oxide) (PEO) with hydroxyl group on repeated monomer as macroinitiator and Sn(Oct) 2 as catalyst, then amphiphilic graft copolymers PEO-g-PCL were obtained. By changing the ratio of monomer and macroinitiator, a series of PEO-g-PCL with well-defined structure, molecular weight control, and narrow molecular weight distribution were prepared. The expected intermediates and final products were confirmed by 1 H NMR and GPC analyzes. In addition, these amphiphilic graft copolymers could form spherical aggregates in aqueous solution by self-assemble, which were characterized by transmission electron microscopy, and the critical micelle concentration values of graft copolymers PEO-g-PCL were also examined in this article.

show abstract

“…Expanding on HIV research, various complexes have been synthesized with curdlan sulfate in order to enhance the efficacy of the polysaccharide. Some prominent examples include covalent conjugation of azidothymidine to curdlan sulfate for drug delivery to the lymph nodes and bone marrow [83] and conjugation of fullerene C60 with curdlan for combining their anti-HIV effects [84].…”

Section: Infection Preventionmentioning

confidence: 99%

1,3-Beta-Glucans: Drug Delivery and Pharmacology

Verma¹,

Gu²

2012

The Complex World of Polysaccharides

View full text Add to dashboard Cite

Syntheses and characterization of water‐soluble C₆₀–curdlan sulfates for biological applications

Cited by 10 publications

References 13 publications

Buckyballs

Buckyballs

Synthesis and characterization of a novel amphiphilic poly (ethylene glycol)–poly (ε-caprolactone) graft copolymers

1,3-Beta-Glucans: Drug Delivery and Pharmacology

Contact Info

Product

Resources

About

Syntheses and characterization of water‐soluble C60–curdlan sulfates for biological applications

Cited by 10 publications

References 13 publications

Buckyballs

Buckyballs

Synthesis and characterization of a novel amphiphilic poly (ethylene glycol)–poly (ε-caprolactone) graft copolymers

1,3-Beta-Glucans: Drug Delivery and Pharmacology

Contact Info

Product

Resources

About

Syntheses and characterization of water‐soluble C₆₀–curdlan sulfates for biological applications