Syntheses, crystal structures and DNA binding potential of copper(II) carboxylates

Synthesis, characterization, antioxidant, antileishmanial, anticancer, DNA and theoretical SARS-CoV-2 interaction studies of copper(II) carboxylate complexes

“…These bond lengths are comparatively shorter than the respective bond lengths reported for bis(2-fluorobenzoate) copper(II) {Cu—O = 1.949-2.126 Å} [55] . The Cu—N = 2.2009 (17) Å bond length for the axial ancillary ligand was found to be 0.05 Å longer than the one previously observed in [pyCu(µ 2 -OOCCH 2 C 6 H 4 R) 4 Cupy] with Cu—N = 2.157(2) Å [36] . The bond angles centered at the copper ions, i.e.…”

“…The presence of coordinated deprotonated carboxylate ligands in the complex spectra was also supported by the appearance of new medium intensity bands at 428 and 434 cm –1 for complexes 1 and 2 , respectively. The coordination of 2-methyl pyridine to copper centers is reflected by the medium intensity bands at 592 and 593 cm –1 in the spectra of complexes 1 and 2 , respectively, owing to the newly established Cu-N bonds and concomitant decrease in the vibration frequencies of the v C=N bond [ 2 , 36 ]. The presence of 2-methyl pyridine was also supported by the strong pyridyl ring vibration at 740 and 750 cm –1 in complexes 1 and 2 , respectively [2] .…”

“…Here we show that varying the electronic structures of the comparatively small phenyl acetic acids by halogen substituent based modulation together with appropriate pyridine co-ligands, can lead to the formation of either of such complex types selectively. The distinct combinations of carboxylates with N-donor ligands not only result in various complexes with a range of geometries but also (fine-)tunes their chemical thermal, magnetic and biological properties [ 2 , 5 , 35 , 36 ].…”

Thermodynamics of Metal–Acetate Interactions

“…Experimental studies indicate that copper can establish diverse complexes with carboxylate ligands, commonly serving as bidentate ligand. 65 However, there has also been the observation of an ongoing shift between monodentate and bidentate bonding modes in carboxylate. 64 Additionally, in the Cu(II) complex with Hmbm (1-methyl-1H-benzo[d]imidazol-2-yl)methanol, acetate coordinates with the metal ion in a monodentate fashion.…”

Heterometallic decanuclear [Fe6–Ln4] coordination clusters with enzymatic mimic activity: Synthesis, structures, magnetic properties, and evaluation of catecholase activity

“…[29][30][31] Besides aminoalcohols, carboxylates also have diversity in coordination modes and can be considered as well as supportive ligands. [32][33][34] The aminoalcohols are also used with various 3d metal ions in catecholase activity. [10,14,16] Out of various types of aminoalcohols, H 2 mdea ligand is peculiar, and its alkoxide arms also can act as a bridging ligand to generate a variety of structural motifs and to produce diversity in nuclearity.…”