Syntheses ofN‐[3‐(1‐methyl‐1H‐2‐imidazolyl)propyl]benzamides andN‐[3‐(1‐methyl‐1H‐2‐imidazolyl)propyl]benzenesulfonamides

Abstract

A series of substituted N‐(4‐substituted‐benzoyl)‐N‐[3‐(1‐methyl‐1H‐imidazol‐2‐yl)propyl]amines (13) and N‐arylsulfonyl‐N‐[3‐(1‐methyl‐1H‐imidazol‐2‐yl)propyl]amines (14) were prepared from the reaction of 3‐(1‐methyl‐1H‐imidazol‐2‐yl)propan‐1‐amine (7) with substituted benzoyl chloride or substituted‐benzene sulfonyl chloride respectively. Compound 7 was prepared by two independent methods.

Designing Advanced Filtration Media through Metal Additive Manufacturing

“…During recent years, there have been intense investigations of different classes of thiadiazole compounds many of which are known to possess interesting biological properties such as antibacterial, antituberculosis, and anticonvulsant activities [1–3]. Imidazole nucleus has a vital rule and substituted imidazoles are known to possess several biological activities, and their antimicrobial properties have been largely described [4–6]. As a part of an extensive search for finding new antimicrobial agents, we have recently reported several classes of broad‐spectrum antibacterial agents from 1,3,4‐thiadiazole series [7–9].…”

Synthesis of novel 2‐(2‐methylsulfonyl‐1‐methyl‐1H‐imidazol‐5‐yl)‐5‐(alkylsulfonyl)‐1,3,4‐thiadiazoles

“…During recent years, there have been intense investigations of different classes of thiadiazole compounds many of which are known to possess interesting biological properties such as antibacterial, antituberculosis, and anticonvulsant activities [1][2][3]. Imidazole nucleus has a vital rule and substituted imidazoles are known to possess several biological activities, and their antimicrobial properties have been largely described [4][5][6]. As a part of an extensive search for finding new antimicrobial agents, we have recently reported several classes of broad-spectrum antibacterial agents from 1,3,4-thiadiazole series [7][8][9].…”