Synthesis and anti‐inflammatory effect of morachalcone B, morachalcone C, and analogs

Abstract

An efficient method to synthesize morachalcones B and C (1 and 2) is described. Rap−Stoermer condensation and 1,3‐prenyl rearrangement were used as two key synthetic methods. Morachalcone C was obtained by photo‐oxygenation of morachalcone B. Morachalcones B and C showed moderate anti‐inflammatory activity.