Synthesis and anticancer mechanisms of four novel platinum(ii) 4′-substituted-2,2′:6′,2′′-terpyridine complexes

Abstract

Mitophagy, a selective autophagic process, has emerged as a pathway involved in degrading dysfunctional mitochondria. Herein, new platinum(II)-based chemotherapeutics with mitophagy-targeting properties were proposed. Four novel binuclear anticancer Pt(II) complexes...