Synthesis and Antieancer Activity of Novel Cyclic N-Hydroxyureas

Investigation of the adsorption behavior of the anti-cancer drug hydroxyurea on the graphene, BN, AlN, and GaN nanosheets and their doped structures via DFT and COSMO calculations

“…14 However, due to its lack of selectivity, it has some adverse effects, such as gastrointestinal disturbance, bone marrow suppression, and dermatological reactions. 6,15 The main purpose of chemotherapy is to destroy cancerous cells only; however, it also causes damage to normal cells, resulting in some adverse effects, such as fatigue, hair loss, nausea, and vomiting. 16 To minimize the side effects and increase the selectivity of drugs, researchers are trying to implement a way in which nanomaterials can be used as drug carriers.…”

“…14 However, due to its lack of selectivity, it has some adverse effects, such as gastrointestinal disturbance, bone marrow suppression, and dermatological reactions. 6,15…”

Protective potential of royal jelly against hydroxyurea -induced hepatic injury in rats via antioxidant, anti-inflammatory, and anti-apoptosis properties

“…In addition, HUD is used as an anti-tumor drug to treat various malignancies [3] such as Melanoma; Leukemia; Ovarian cancer; Head and neck cancer [4]. It is being utilized as an antineoplastic agent in the treatment of malignant melanoma, head and neck malignancies, brain tumors, and a few non-malignant illnesses in combination with radiation therapy [5,6].…”