Synthesis and antifungal properties of sulfanilamide derivatives of chitosan

Zhong, Zhimei; Chen, Rong; Xing, Ronge; Chen, Xiaolin; Liu, Song; Guo, Zhanyong; Ji, Xia; Lin, Wang; Li, Pengcheng

doi:10.1016/j.carres.2007.07.015

Cited by 69 publications

(38 citation statements)

References 19 publications

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“…(No et al 2002;Tin et al 2009), fungi (A. niger, Alternaria alternata, Alternaria solani, Phomopsis asparagi, Rhizopus stolonifer, Rhizopus oryzae, Phytophthora capsici, Phytophthora parasítica, Verticillium dahlia, Colletotrichum orbiculare, Exserohilum turcicum, Pyricularia oryzae, Botrytis cinerea, Fusarium oxysporum, Fusarium graminearum, Fusarium sulphureum, Fusarium solani, Candida albicans, Neurospora crassa, Penicillium expansum, Penicillum digitatum, etc.) (Reddy et al 1998;Guerra-S 0 anchez et al 2009;Zhong et al 2007;Ziani et al 2009;Falcón et al 2008;Kong et al 2010;Yong-cai et al 2009;Lafontaine and Benhamou 1996;Lauzardo 2009;Rane and Hoover 1993;Ting et al 2007;Xu et al 2007;Palma-Guerrero et al 2009;Pacheco et al 2008) and parasites (Trichomonas gallinae, E. granulosus, Cryptosporidium parvum, Philasterides dicentrarchi, etc.) (Tavassoli et al 2012;Fakhar et al 2013;Brown and Emelko 2008;Parama et al 2005).…”

Section: Discussionmentioning

confidence: 99%

The anti-giardial effectiveness of fungal and commercial chitosan against Giardia intestinalis cysts in vitro

et al. 2014

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Chitosan with poly-N-acetylglucosamine sequences is a deacetylated derivative of chitin that can be found in the exoskeletons of crabs, shrimp and lobsters, the cuticles of insects and the cell walls of fungi. The aim of the present study was to compare the effects of fungal chitosan (FC) prepared from the cell walls of Penicillium viridicatum and Penicillium aurantiogriseum with commercially available chitosan (CC) against Giardia intestinalis cysts in vitro. The giardia cysts were isolated using a sucrose method. Four concentrations (50, 100, 200 and 400 lg/ml) of each type of prepared chitosan were applied for 10, 30, 60 and 180 min. The viability of the cysts was checked via 0.1 % eosin staining. Our results indicate that P. viridicatum (with a 47.5 % DD) and P. aurantiogriseum (with a 47.3 % DD) at different concentrations after 180 min precipitated, respectively, 56, 69, 81 and 100 %, and 63, 75, 86 and 100 % mortality rates. CC (with a 54 % DD) showed 79, 84, 93 and 100 % mortality rates. In conclusion, both FC and CC at 400 lg/ml concentrations after 180 min of exposure showed the most potent effect against G. intestinalis cysts. Accordingly, chitosan could be suggested as a new natural nanoform agent for future research in the safe and effective treatment of Giardia infections.

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Section: Discussionmentioning

confidence: 99%

The anti-giardial effectiveness of fungal and commercial chitosan against Giardia intestinalis cysts in vitro

et al. 2014

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“…As for the FT-IR spectra was concerned: first, the big translocation between 3536 and 3236 cm −1 with a peak at 3386 cm −1 of original inulin changed to between 3520 and 3380 cm −1 with a peak at 3400 cm −1 of the inulin derivatives and at the same time, the breadth of the translocation of the product narrowed compared with the spectra of inulin. A reasonable explanation of these two shifts could be the single O-H group stretching vibration in inulin transformed to O-H group combining with N-H stretching vibration group in OAEIL and the decrease of hydroxy groups of the product, which were used to connect ethylene imine during reaction stage (Zhong et al, 2007). Second, the new peaks at 1592 cm −1 and 1083 cm −1 appeared at the spectra of the product, respectively suggesting the new group -NH 2 and the new ether bond ) of the derivatives Zhong et al, 2007).…”

Section: Chemical Synthesesmentioning

confidence: 99%

“…A reasonable explanation of these two shifts could be the single O-H group stretching vibration in inulin transformed to O-H group combining with N-H stretching vibration group in OAEIL and the decrease of hydroxy groups of the product, which were used to connect ethylene imine during reaction stage (Zhong et al, 2007). Second, the new peaks at 1592 cm −1 and 1083 cm −1 appeared at the spectra of the product, respectively suggesting the new group -NH 2 and the new ether bond ) of the derivatives Zhong et al, 2007). The structure of the OAEIL was further confirmed by 1 HNMR (Fig.…”

Section: Chemical Synthesesmentioning

confidence: 99%

Highly efficient synthesis and antioxidant activity of O-(aminoethyl)inulin

Ren¹,

Liu²,

Dong³

et al. 2011

Carbohydrate Polymers

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“…Being a highly insoluble and chemically rather unreactive material, chitin has a much lower applicability than chitosan. Recently, there has been growing interest in the chemical modification of chitosan and chitin (e.g., [32][33][34][35]) in order to improve their solubility and extend their applications (e.g., [7,19,36,37]). …”

Section: Introductionmentioning

confidence: 99%

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

et al. 2011

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Abstract:The physicochemical nature of chitin and chitosan, which influences the biomedical activity of these compounds, is strongly related to the source of chitin and the conditions of the chitin/chitosan production process. Apart from widely described key factors such as weight-averaged molecular weight (M W ) and degree of N-acetylation (DA), other physicochemical parameters like polydispersity (M W /M N ), crystallinity or the pattern of acetylation (P A ) have to be taken into consideration. From the biological point of view, these parameters affect a very important factor-the solubility of chitin and chitosan in water and organic solvents. The physicochemical properties of chitosan solutions can be controlled by manipulating solution conditions (temperature, pH, ionic strength, concentration, solvent). The degree of substitution of the hydroxyl and the amino groups or the degree of quaternization of the amino groups also influence the mechanical and biological properties of chitosan samples. Finally, a considerable research effort has been directed towards developing safe and efficient chitin/chitosan-based products because many factors, like the size of nanoparticles, can determine the biomedical characteristics of medicinal products. The influence of these factors on the biomedical activity of chitin/chitosan-based products is presented in this report in more detail. OPEN ACCESSPolymers 2011, 3 1876

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Synthesis and antifungal properties of sulfanilamide derivatives of chitosan

Cited by 69 publications

References 19 publications

The anti-giardial effectiveness of fungal and commercial chitosan against Giardia intestinalis cysts in vitro

The anti-giardial effectiveness of fungal and commercial chitosan against Giardia intestinalis cysts in vitro

Highly efficient synthesis and antioxidant activity of O-(aminoethyl)inulin

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

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