Synthesis and Antimicrobial Activity of Novel Phosphorus Heterocycles with Exocyclic P—C Link.

Reddy, P. Vasu Govardhana; Kiran, Y. B.; Reddy, C. Suresh; Reddy, C. Devendranath

doi:10.1002/chin.200433191

Cited by 9 publications

(13 citation statements)

References 1 publication

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“…Brugnatelli isolates Alloxan from uric acid 1832. Dobereiner produces furfural (afuran) by treating starch with sulfuric acid1834: Runge obtains pyrrole ("fiery oil") by dry distillation of bones1906 6,7 . Friedlander synthesizes indigo dye, allowing synthetic chemistry to displace a large agricultural industry1936: Treibsisolates chlorophyll derivatives from crude oil, explaining the biological origin of petroleum1951: Chargaff's rules aredescribed, highlighting the role of heterocyclic compounds (purines and pyrimidines) in the genetic code 8 compounds are widely distributed in nature.…”

Section: History Of Heterocyclic Chemistrymentioning

confidence: 99%

Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’

Shaikh

Farooqui²,

Satpute³

et al. 2018

J. Drug Delivery Ther.

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Heterocyclic compounds have a role in most fields of sciences such as medicinal chemistry, biochemistry also another area of sciences. More than 90% of new drugscontain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. Compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields.Most active heterocycles that have shown considerable biological actions as antifungal, anti-inflammatory, antibacterial, anticonvulsant, antiallergic, herbicidal, anticancer activity. There is always a strong need for new and efficient processes in synthesizing of new Heterocycles.Alum have been used as a novel catalyst in the synthesis of Schiff’s bases. Synthesized Schiff’s bases are free from use of ICH class 1 and Class 2 solvents and also free from structural alerts genotoxic impurities. This review highlights on various aspects of heterocyclic compounds with its biological activity & regulatory assessment based on the ‘International Regulatory Standards’. Keywords: Heterocycles. Nitrogen containing compounds Biological activity, History, Regulatory assessment, International Regulatory Standards

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Section: History Of Heterocyclic Chemistrymentioning

confidence: 99%

Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’

Shaikh

Farooqui²,

Satpute³

et al. 2018

J. Drug Delivery Ther.

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“…These indicators contribute to the widespread use of the derivatives of this class in various fields [1]. The literature describes a huge potential for the broad-spectrum pharmacological activities, in particular, antiviral [2], antifungal and antibacterial [3], antiinflammatory and analgesic [4], anti-stress, anti-cancer, anti-tuberculosis [5] activities.…”

Section: Introductionmentioning

confidence: 99%

PROSPECTS FOR THE CHEMISTRY OF IMIDAZOLE DERIVATIVES (Review)

Kaldybayeva¹,

Malmakova²,

Yu³

et al. 2022

Chem. J. of Kaz.

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The problem of creating new effective domestic pharmacological preparations, including the development of the methods for obtaining biologically active substances in compliance with the “green chemistry” principles, are among the priority areas for the development of chemical science. The choice of an initial molecule, which carries the potential of biological activity, is the guarantor of a successful experimental search. Imidazole derivatives occupy a unique place in the medicinal chemistry. An imidazole cycle is part of the natural compounds such as histamine, biotin, some alkaloids and nucleic acids, and is a structural fragment of medicinal preparations. The goalof the present review is to analyze the publications on the chemistry of imidazole derivatives with an emphasis on the methods of obtaining biologically active and other practically useful molecules with an obligatory imidazole cycle. The objects of the study:imidazole derivatives. The examples of the routes of synthesizing imidazole derivatives, as well as the compounds of interest for the medicinal chemistry, agriculture, and other fields, which have been published in the scientific and technical literature since 2000, have been presented. Conclusion.The studies in the field of searching for new highly effective preparations among imidazole derivatives are relevant and promising. The most important stage in this search is the directed synthesis of the substances with the specified, practically useful properties. The range of new practically useful substances in the series of imidazole derivatives has been significantly expanded and replenished thanks to the modern modifications of the classical methods of their obtaining.

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“…9 In addition, they have a prominent application in polymer chemistry as heat stable epoxy resins, fiber reactive dyes and polymers. 10 A literature survey also revealed the importance of 6-heteryl-quinazolin-4(3H)-ones in pharmaceutical chemistry as antihypertensive, 11 antiviral, 12 antitumor 13 and TGFβ type 1 receptor inhibitor to treat many fibrosis. 14 Additionally, these act as size expanded nucleoside which in turn are useful in the study of steric effects of DNA-protein interactions and also served as building blocks for a large size genetic system.…”

Section: Introductionmentioning

confidence: 99%

PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions

Pagilla¹,

Kumar²,

Sunitha

et al. 2020

JSCS

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Synthesis and Antimicrobial Activity of Novel Phosphorus Heterocycles with Exocyclic P—C Link.

Abstract: For Abstract see ChemInform Abstract in Full Text.

Cited by 9 publications

References 1 publication

Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’

Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’

PROSPECTS FOR THE CHEMISTRY OF IMIDAZOLE DERIVATIVES (Review)

PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions

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