Synthesis and Antimicrobial Activity of (1-Acetyl/1-Phenyl)-3-{4'-[(4'''-Chlorophenyl) (Phenyl) Methyl Amino] Phenyl}-5-Aryl-Pyrazoline

Abstract

ABSTRACT1-Acetyl-3-{4'-[(4'''-chlorophenyl) (phenyl) methyl amino] phenyl}-5-aryl-pyrazolines (3a-3l) and 1-Phenyl-3-{4'-[(4'''-chlorophenyl) (phenyl) methyl amino] phenyl}-5-aryl-pyrazolines (4a-4l) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram -ve bacteria and fungi. Some of the compounds showed moderate activity in concentration 50 μg/ml. The structure of the products have been elucidated by IR, 1 H-NMR, mass spectral data elemental analysis and Thin layer chromatography.