2008
DOI: 10.1016/j.bmc.2008.10.043
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Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones

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Cited by 41 publications
(19 citation statements)
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“…15) It had been reported to possess important biological activities. Hoettecke et al 16) had prepared 2-alkenylthiochroman-4-ones and tested their antimicrobial activity. Moreover, in our previous work, 17) 1-(4-phenylthiazol-2-yl)-1,4-dihydrothiochroman[4,3-c] pyrazole was synthesized and showed good inhibition for Cryptococcus neoformans.…”
Section: Synthesis Characterization and Antifungal Evaluation Of Novmentioning
confidence: 99%
“…15) It had been reported to possess important biological activities. Hoettecke et al 16) had prepared 2-alkenylthiochroman-4-ones and tested their antimicrobial activity. Moreover, in our previous work, 17) 1-(4-phenylthiazol-2-yl)-1,4-dihydrothiochroman[4,3-c] pyrazole was synthesized and showed good inhibition for Cryptococcus neoformans.…”
Section: Synthesis Characterization and Antifungal Evaluation Of Novmentioning
confidence: 99%
“…Although some synthetic approaches to thiochroman-4-ones, thioflavone, and thiochromones have been reported in literature [ 28 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 ], research on efficient synthesis of 2-substituted thiochroman-4-ones is an underexplored area when compared to O-containing counterparts. Synthetic approaches to 2-substituted thiochroman-4-ones utilizing Friedel-Crafts acylation of thiopropanoic acid [ 56 ], hydrogenation of thiochromones [ 57 , 58 , 59 ], and intramolecular thio-Michael addition [ 60 , 61 , 62 , 63 , 64 , 65 , 66 ] have been reported.…”
Section: Introductionmentioning
confidence: 99%
“…Goth described the antibacterial properties of coumarins for the first time in 1945 when he studied the dicoumarol ( Figure 1 ) [ 18 ]. Some other coumarin derivatives have proven to display antibacterial and antifungal activities [ 19 , 20 , 21 , 22 ]. A study of coumarin derivatives substituted on the pyrone ring indicated that 3-carboxyl derivatives show significant activities [ 23 ].…”
Section: Introductionmentioning
confidence: 99%