Synthesis and antimicrobial activity of some new pyrrole derivatives

Abstract

ABSTRACT. New pyrrole derivatives were synthesized and structures were confirmed by IR, 1 H NMR, 13 C NMR, mass spectra, and elemental analyses data. The reaction was performed by using ordinary condensation type, which enabled to easy work-up and good yield. Synthesized compounds were screened for antimicrobial activity.

Effect of Substitutions on 1, 4‐Dihdropyridines to Achieve Potential Anti‐Microbial Drugs: A Review

“…Compound 30 a & 30 b also against Non‐hemolytic streptococcus & P. aeruginosa gave better activity respectively. However against other tested species the results were not that much significant …”

Montmorillonite KSF Clay Catalyzed Microwave Synthesis of Novel Mannich bases and their Microbial Activity

“…[9][10][11] That the compounds containing amide moiety exhibit a wide range of biological activities. [12][13][14][15][16][17][18][19][20] In the past few years microwave synthesis methods has increased popularity as a non-conventional procedures for fast organic synthesis methods and many researchers have described accelerated organic reactions. In continuation of our research green chemistry program.…”

Synthesis and Pharmacological Evaluation of Some New Chromeno[3,4‐c]pyrrole‐3,4‐dione‐based N‐Heterocycles as Antimicrobial Agents

“…Pyrroles, the third heteroaryls in this introduction, exhibited numerous biological activities, including anticoagulant , antimicrobial , human tumor models , antiviral , and anticonvulsant activities . Based on the aforementioned observation, current investigation of this work was on the synthesis of new pyrrole and 1,4‐dihydropyridine derivatives and evaluated for pharmacological activity.…”