1981
DOI: 10.1007/bf00760665
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Synthesis and antimicrobial properties of Mannich bases in the 2-pyrrolidone and 2-thiopyrrolidone series

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“…If the keto reduction reaction(s) were to be carried out chemically, it would require harsh chemical reduction such as with LiAlH 4 at À70 8C. [30] Our findings suggest that the keto reduction reaction(s) from pre-xyrrolin (enol; 20) or protoxyrrolin (25) into 1 is an interesting model system that warrants further genetic, biochemical and structural investigation. Xyrrolin from Xylaria sp.…”
Section: Discussionmentioning
confidence: 87%
“…If the keto reduction reaction(s) were to be carried out chemically, it would require harsh chemical reduction such as with LiAlH 4 at À70 8C. [30] Our findings suggest that the keto reduction reaction(s) from pre-xyrrolin (enol; 20) or protoxyrrolin (25) into 1 is an interesting model system that warrants further genetic, biochemical and structural investigation. Xyrrolin from Xylaria sp.…”
Section: Discussionmentioning
confidence: 87%