Synthesis and antioxidant studies of novel bi-, tri-, and tetrapodal 9-aryl-1,8-dioxo-octahydroxanthenes

Iniyavan, P.; Sarveswari, S.; Vijayakumar, V.

doi:10.1016/j.tetlet.2015.01.162

Cited by 12 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They are also very useful in laser technologies, uorescent materials for visualization of biomolecules, dyes and photodynamic therapy. 11 Moreover, several polycyclic compounds containing xanthene skeleton have been isolated from natural sources as plant species for their prospective bio-activity. Various methods for the formation of xanthenes derivatives have been reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

Facile fabrication of bimetallic Fe–Mg MOF for the synthesis of xanthenes and removal of heavy metal ions

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Facile fabrication of bimetallic Fe–Mg MOF for the synthesis of xanthenes and removal of heavy metal ions

et al. 2020

View full text Add to dashboard Cite

show abstract

“…72,73 Additionally, they are also useful in materials science as fluorescent materials and dyes and in photodynamic therapy. 74,75 Taking into account that the syntheses of xanthenes, benzoxanthenes, and their derivatives have been reported in the literature, [76][77][78] numerous catalysts were able to produce these compounds. As examples, KF impregnated on a clinoptilolite nanoparticle catalyst was used for the multicomponent condensation reaction among 2-naphthol, benzaldehydes, and 1,3dicarbonyl compounds, 77 and Fe 3 O 4 nanoparticles were also employed as catalysts.…”

Section: Resultsmentioning

confidence: 99%

Rice straw ash extract/glycerol: an efficient sustainable approach for Knoevenagel condensation

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The antioxidant activity of Compound 1 was investigated using the DPPH method [16]. A 0.001 gram of residue was placed into the 10 ml volumetric flask and dissolved into chloroform until the border mark.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Assisted ultrasonic wave of vanillin derivatives synthesis and antioxidant activity using DPPH method

Retnosari¹,

Sari²,

Marfuah³

et al. 2022

CST

View full text Add to dashboard Cite

In recent years, the need for compounds with antioxidant activities have expanded. Generally, the natures of these compounds involve the presence of conjugated double bonds, phenolic groups, and resonance effects on the structure. One of the compounds with the phenolic group is vanillin. It can be modified into the derivative of 1,8-dioxo-octahydroxantene compound due to its aldehyde content. Meanwhile, 1,8-dioxo-octahydroxantene compound has two 2- cyclohexenone rings bound in the pyran ring and one phenolic group, expected to carry more excellent antioxidant activity than vanillin. The 9-(4-hydroxy-3-methoxyphenyl)-3,4,5,6,7,9- hexahydro -1H-xantene-1,8(2H)-dione (Compound 1) was synthesized from 1,3- cyclohexanedione and vanillin through Knoevenagel's condensation reaction aided with an acid catalyst with a single reaction phase. Besides, green chemistry was adopted in this study using environmentally friendly catalysts from lime juice and ultrasonic wave. The synthesized compounds' structure was confirmed through the spectrophotometer IR, GC-MS, and 1H-NMR spectrometer, while its antioxidant activity was tested using the DPPH method. The reaction occurred with and without lime juice catalyst, producing yields of 6.65% and 70.58%, respectively. The results of the antioxidant activity test suggest that Compound 1 carries substantially robust antioxidant activities, with IC50 of 0.99 ppm.

show abstract

Synthesis and antioxidant studies of novel bi-, tri-, and tetrapodal 9-aryl-1,8-dioxo-octahydroxanthenes

Cited by 12 publications

References 33 publications

Facile fabrication of bimetallic Fe–Mg MOF for the synthesis of xanthenes and removal of heavy metal ions

Facile fabrication of bimetallic Fe–Mg MOF for the synthesis of xanthenes and removal of heavy metal ions

Rice straw ash extract/glycerol: an efficient sustainable approach for Knoevenagel condensation

Assisted ultrasonic wave of vanillin derivatives synthesis and antioxidant activity using DPPH method

Contact Info

Product

Resources

About