Synthesis and application of chitosan thiourea derivatives as chiral stationary phases in HPLC

Hybridization of helical poly(phenylacetylene)s bearing l-proline tripeptide pendants into porous silica microspheres as a solvent-tolerable chiral stationary phase for liquid chromatography

“…5,6 Critical to HPLC-based separation of enantio-mers is the chiral recognition ability of the chiral stationary phase (CSP). 7,8 Looking beyond polysaccharide-based CSPs, some synthetic optically active polymers can also exhibit excellent chiral recognition ability, and they have been used in the analysis and separation of enantiomers. [9][10][11][12][13][14] In multitudinous synthetic optically active polymers, one-handed helical poly ( phenylacetylene) has attracted extensive attention because of its particular helical structure and properties.…”