Beckmann rearrangement has been quite successful in the preparation of many medicinally potent scaffolds. In synthetic organic chemistry, the Beckmann rearrangement is quite popular, caprolactam is synthesized from cyclohexanone oxime on a large scale for Nylon‐6 production. The function of numerous catalysts and media in the Beckmann rearrangement has been discussed in depth in this review. In the last 20 years, Beckmann rearrangement catalysis has evolved from a potentially hazardous to a more environmentally friendly catalyst, as a result of greater usage. Catalytic performance and synthetic performance of various catalytic systems have been re‐evaluated in the present review article.
Beckmann rearrangement has been quite successful in the preparation of many medicinally potent scaffolds. In synthetic organic chemistry, the Beckmann rearrangement is quite popular, caprolactam is synthesized from cyclohexanone oxime on a large scale for Nylon‐6 production. The function of numerous catalysts and media in the Beckmann rearrangement has been discussed in depth in this review. In the last 20 years, Beckmann rearrangement catalysis has evolved from a potentially hazardous to a more environmentally friendly catalyst, as a result of greater usage. Catalytic performance and synthetic performance of various catalytic systems have been re‐evaluated in the present review article.
“…Pyridyl oximes have the general formula (py)C(R)NOH, where py is a pyridyl group attached to the oxime carbon atom and R can be a donor or a non-donor group [4]. Pyridyl oximes ligands represent one of the most widely utilized classes of ligands in coordination chemistry [5].…”
“…[15][16][17][18] More commonly, synthetic transformations such as selenenylations, selenocyclizations and 2,3-sigmatropic rearrangements have been successfully achieved using these reagents under mild reaction conditions. [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] The application of these reagents in catalysis makes them more suitable reagents in organic synthesis. [34][35][36][37][38][39] Several books, [1][2][3][4][5][6][7][41][42][43] book chapters [8][9][10][11][44][45][46][47][48] and review articles [49][50][51][52][53]…”
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