2024
DOI: 10.1002/slct.202400715
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Synthesis and Biofunctional Properties of NaBr/H2O2‐Induced Brominated Uracil Derivatives

Shivangi,
Subrata Das,
Susital Mal
et al.

Abstract: Bromouracil derivatives are synthesized using an environmentally acceptable bromination protocol involving NaBr as a promoter. A minimum of 1.5 equivalent NaBr was required to reach the maximum yield. The reactions were conducted in an acidic medium in the presence of H2O2 under ambient conditions. We successfully synthesized ten novel 5‐bromouracil derivatives available in our laboratory and characterized them using various spectroscopic methods such as 1H‐NMR, 13C‐NMR, and SC‐XRD. All the derivatives are scr… Show more

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