2018
DOI: 10.1007/s11164-018-3483-0
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Synthesis and biological activity of novel benzoazoles, benzoazines and other analogs functionalized by 2,4-dihydroxyphenyl moiety

Abstract: Novel benzoazoles, benzoazines, benzothiazoles, benzothiazines and other related compounds possessing a 2,4-dihydroxyphenyl moiety were prepared. The compounds were obtained by the reaction of sulfinylbis[(2,4-dihydroxyphenyl)methanethione]s with the appropriate heterocyclic amines or hydrazines. The structures of the compounds were proved by IR, 1 H NMR, and mass spectral data. Human cancer lines, Candida species and phytopathogenic fungi were used for the evaluation of biological potency of compounds. Additi… Show more

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Cited by 6 publications
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“…Arylbenzothiazole is an important structural motif which can be seen in many organic compounds. 2-Arylbenzothiazole derivatives always show some bioactivities and are used as pharmaceuticals, such as antineoplastic agents, [1] neurological drugs, [2] hematology drugs [3] and cardiovascular drugs [4] (Figure 1). Scientists are highly concerned about the synthesis of 2-arylbenzothiazole derivatives, [5] and always try to develop some efficient synthetic methods.…”
Section: Introductionmentioning
confidence: 99%
“…Arylbenzothiazole is an important structural motif which can be seen in many organic compounds. 2-Arylbenzothiazole derivatives always show some bioactivities and are used as pharmaceuticals, such as antineoplastic agents, [1] neurological drugs, [2] hematology drugs [3] and cardiovascular drugs [4] (Figure 1). Scientists are highly concerned about the synthesis of 2-arylbenzothiazole derivatives, [5] and always try to develop some efficient synthetic methods.…”
Section: Introductionmentioning
confidence: 99%