“…Similarly, acting as both reactant and reaction medium, water is also expected to have a positive effect on the epoxide hydration. When encountering an attack by some nucleophilic reagents, e.g., water, amines, alcohols, and sulfides, etc., the C–O bond in the three-membered heterocycle of the epoxide tends to be broken and thus forms a stable addition compound. , Figure b gives the catalytic results of the cyclohexene oxide hydration with different ratios of water/epoxide (2/1, 5/1, 10/1, 20/1, and 40/1). The hydration reaction was greatly accelerated by increasing the relative ratio of water, and the TOF also reached a high value of 122.2 mol diol ·mol Fe –1 ·h –1 when n (water)/ n (epoxide) = 40/1 was selected, which is nearly 8 times higher than that using n (water)/ n (epoxide) = 2/1.…”