Synthesis and characterization of 5- and 7-donor Schiff base ligands and spectroscopic evidence for tautomerism: A crystal structure showing tautomeric forms within one ligand

Ogutu, Hezron; Saban, Waheed; Malgas-Enus, Rehana; Luckay, Robert C.

doi:10.1016/j.molstruc.2019.02.054

Cited by 5 publications

(3 citation statements)

References 27 publications

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“…The final product was characterized by 1 H NMR and FT-IR spectroscopy. 28 1 H NMR (300 MHz, DMSO-d 6 ) δ: 2.9 (4H, -CH 2 ), 3.6 (4H, -CH 2 ), 6-7.5 (8H, H-aromatic), 8.28 (2H, H-CvN), 13-13.2 (2H, OH) ppm (Fig. S1 †).…”

Section: Catalyst Preparationmentioning

confidence: 99%

A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water

Aghajani,

Mohammadikish

2024

Dalton Trans.

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Section: Catalyst Preparationmentioning

confidence: 99%

A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water

Aghajani,

Mohammadikish

2024

Dalton Trans.

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“…They possess various uses such as in photochromic, hydrometallurgy studies, and making of dyes. [3][4][5] They have good biological features and have thus been used in various catalytic and gas storage studies and anti-cancer and anti-microbial studies. [6,7] Carbonic anhydrases (hCAs; EC 4.2.1.1) are necessary for almost all forms of life, as they are involved in the conversion of water and carbon dioxide to protons and bicarbonates.…”

Section: Introductionmentioning

confidence: 99%

“…Since Schiff base ligands are strong chelators, they can form stable coordination complexes with transition metal ions. They possess various uses such as in photochromic, hydrometallurgy studies, and making of dyes [3–5] . They have good biological features and have thus been used in various catalytic and gas storage studies and anti‐cancer and anti‐microbial studies [6,7] …”

Section: Introductionmentioning

confidence: 99%

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

et al. 2021

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Schiff bases display superior features for many areas, such as significant intermediates in industrial biological, pharmacological, catalytic and optical properties, organic synthesis, and coordination chemistry. The pre‐synthesized two Schiff base ligands (HL1 and HL2) and their bidentate metal complexes (Co(L1)2, Cu(L1)2, Ni(L1)2, Co(L2)2, Cu(L2)2, and Ni(L2)2) were tested for their inhibition activities on acetylcholinesterase (AChE) and human carbonic anhydrase (hCA I and hCA II) isoforms. The transition metal complexes of bidentate Schiff base ligands displayed the potent inhibition effect with KI constants ranging from 16.39±0.15 to 88.63±0.27 nM and 9.32±0.13 to 33.66±0.57 nM for hCA isoenzymes and AChE, respectively. The compound Cu(L1)2 for hCA I and Ni(L2)2 for AChE and hCA II had the highest inhibitory effect. Besides, the molecular docking analyses of the most active complexes (Cu(L1)2 and Ni(L2)2) were performed to understand the binding interactions on the enzymes’ binding sites. According to both in vitro and in silico analysis results, all the compounds were potential inhibitors of AChE and hCA I, II isoenzymes.

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Design, synthesis and spectroscopic characterization of mixed N- and O-donor Schiff base ligands (N2O3): Crystal structures of free ligands

Ogutu

Saban

Malgas-Enus

et al. 2020

Journal of Molecular Structure

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Synthesis and characterization of 5- and 7-donor Schiff base ligands and spectroscopic evidence for tautomerism: A crystal structure showing tautomeric forms within one ligand

Cited by 5 publications

References 27 publications

A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water

A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

Design, synthesis and spectroscopic characterization of mixed N- and O-donor Schiff base ligands (N2O3): Crystal structures of free ligands

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Synthesis and characterization of 5- and 7-donor Schiff base ligands and spectroscopic evidence for tautomerism: A crystal structure showing tautomeric forms within one ligand

Cited by 5 publications

References 27 publications

A stable hybrid catalyst (POM-PPPh3/L/Ni) for the reduction of toxic nitroarene compounds in water

A stable hybrid catalyst (POM-PPPh3/L/Ni) for the reduction of toxic nitroarene compounds in water

Transition‐Metal Complexes of Bidentate Schiff‐Base Ligands: In Vitro and In Silico Evaluation as Non‐Classical Carbonic Anhydrase and Potential Acetylcholinesterase Inhibitors

Design, synthesis and spectroscopic characterization of mixed N- and O-donor Schiff base ligands (N2O3): Crystal structures of free ligands

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A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water

A stable hybrid catalyst (POM-PPPh₃/L/Ni) for the reduction of toxic nitroarene compounds in water