Synthesis and Characterization of BHT-Derived tert-Butyl Dendrons

Abstract

A series of 3,5-poly(aryl ether) dendrons was prepared up to the third generation using inexpensive 3,5-di-tert-butyl-4-hydroxytoluene (BHT, 1) as a starting material.

Synthesis of Fréchet-type Dendrimers with Tripodal Core via Staudinger/Aza-Wittig Reactions

“…The poly(benzyl ether) dendrons, now frequently referred to as Fréchet-type dendrons, was selected because they are relatively readily accessed and exhibit the chemical stability associated with ether linkages. [19][20][21][22][23][24][25][26][27][28] Here we present the convergent synthesis of tripodal Fréchet-type dendrimers by trimerization of aldehyde-dendrons via Staudinger/ aza-Wittig reactions using tripodal core, 1,3,5-tris-(3-azidopropoxy)-benzene.…”

Frustration of Condensed Phase Aggregation of Naphthalocyanine by Dendritic Site-Isolation

“…The synthesis of dendritic Ncs utilized 6,7-disubstituted naphthalonitriles 12 and 13 as precursors (Scheme ). The synthetic route leading to these naphthalonitriles started from dimethyl 4,5-dihydroxyphthalate 5 , onto which the previously synthesized dendritic alcohols 3 and 4 were introduced via the Mitsunobu protocol (Scheme ). The obtained diesters 6 and 7 were reduced to the corresponding 1,2-dimethanols ( 8 and 9 ), and subsequent Swern oxidation provided the disubstituted dendritic phthalaldehydes 10 and 11 .…”