Synthesis and characterization of biocompatible poly(ethylene glycol)-functionalized polyurethane using click chemistry

Antifouling polyurethanes to fight device-related staphylococcal infections: synthesis, characterization, and antibiofilm efficacy

“…Particularly, repelling activity (antifouling) is shown when polymers are hydrophilic, electrically neutral, and able to accept hydrogen bonds (Ostuni et al, 2001). Among the antifouling polymers, poly(ethylene glycol) (PEG) is the most investigated and used either alone or grafted to polymeric surfaces (Li et al, 2010;Rana et al, 2010).…”

“…Notwithstanding the presence of soft domains that are hydrophilic and flexible, polyurethanes, if not properly functionalized, are not able to effectively counteract bacterial adhesion. Their coating or grafting with hydrophilic polymers is the most common strategy to improve their surface wettability (Orban et al, 1999;Sagnella & Mai-Ngam, 2005;Perrino et al, 2008;Chen et al, 2009;Rana et al, 2010) and thus their antiadhesive properties vs. bacteria (Park et al, 1998;Morra & Cassinelli, 1999). Overall, very few data are available on the ability of these functionalized polyurethanes to control microbial adhesion on and surface colonization of medical devices.…”

Synthesis and characterization of triazole rich polyether polyols using click chemistry for highly branched polyurethanes

“…In this regard, 1,2,3-Triazoles can extensively be used to attain better properties in various fields of polymer & material science such as corrosion protection [4], fabric coatings [5], biodegradable polymers [6], energetic binders [7], anti-microbial coatings [8], biomedical applications [9] and so on. 1,2,3-Triazoles have been of great interest in the area of polymer chemistry due to its versatile applicability to the synthesis of functional polymers [10,11].…”

Development of shape memory polyurethane based on polyethylene glycol and liquefied 4,4′‐diphenylmethane diisocyanate using a bulk method for biomedical applications

“…PEG based SMPUs (PEGSMPUs) are widely reported in the literature . For example, Mondal and Hu synthesized SMPU with PEG3400, and they studied the influence of PEG3400 on shape memory properties.…”

“…Meng and Hu synthesized smart phase change materials and developed a temperature‐regulating fiber by employing PEG soft segments. Rana et al synthesized one kind of biocompatible PEG‐functionalized polyurethane using click chemistry. Chung et al synthesized one kind of new SMPU by some PEG spacers; in addition to thermally induced shape recovery, the synthesized polyurethane also exhibited water‐triggered shape memory behaviors .…”