Synthesis and characterization of biodegradable and cytocompatible polyurethane-bovine-derived hydroxyapatite biomaterials

Parveen, Shaista; Sultan, Misbah; Sajid, Muhammad Imran; Jubeen, Farhat; Parveen, Shagufta; Bibi, Ismat; Safa, Yusra

doi:10.1007/s00289-021-03622-z

Cited by 11 publications

(7 citation statements)

References 23 publications

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“…In the case of the PUR2 sample, the 2nd thermal response is visible at 363.5 °C with 39.22% weight loss, followed by 3rd step at 393.9 °C with 36.10% of weight loss. A similar two-stage thermal decomposition was reported for PURs [ 37 , 38 ].…”

Section: Resultssupporting

confidence: 76%

“…The residue after testing was 6.95%, 12.34%, and 16.59% of the original sample weight for the series PUR2, PUR3, and PUR1, respectively. The heat resistance of the investigated PURs is similar to the reported PURs based on the comparison of the main stage of degradation (2nd) [ 38 , 39 ]. In the studied series, sample PUR1 is the most thermally stable, which is the outcome of the presence of the aromatic ring in the primary diole structure.…”

Section: Resultssupporting

confidence: 75%

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New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

et al. 2021

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Polyether-pentols (PEPOs) were synthesized from glycidyl ethers and butylene oxide with the application of tripotassium salts of 2,2,6,6-tetrakis(hydroxymethyl)cyclohexanol (HMCH) activated 18C6 for ring-opening polymerization (ROP). The construction of the applied initiator system reflects the ability of crown ether to influence the degree of ion-pair separation with an increased activating effect. As a result formation of bi- or trimodal polymers was observed with molar masses in the range of (Mn = 1200–6000). The observed multi-fraction composition is prescribed to the formation of ionic aggregates with different reactivities during polymerization. The mechanism of the studied processes is discussed. The obtained PEPOs served for a crosslinked PUR synthesis, for which the hydrogen bond index for coupling of hard segments was calculated. Additionally, the range of phase separation was calculated that was higher for PUR-containing aromatic rings as the substituent.

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Section: Resultssupporting

confidence: 76%

Section: Resultssupporting

confidence: 75%

New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

et al. 2021

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“…3(b) shows the XRD curves of CS, Fe 3 O 4 , PUR and the 0.3% PUR/CS–Fe 3 O 4 magnetic nanocomposite, where the peaks at 2 θ = 35.5, and 62.5° correspond to the (311), and (440) diffraction planes of the Fe 3 O 4 cubic-tip crystal structure, respectively. 33,35 These data indicate that the CS–Fe 3 O 4 magnetic nanocomposite exhibits the same physicochemical properties as those of standard Fe 3 O 4 nanoparticles. In addition, a broad peak at 2 θ = 22.5° indicates a typical hypocrystalline structure.…”

Section: Resultsmentioning

confidence: 62%

Preparation and performance study of a reactive polyurethane hot-melt adhesive/CS–Fe₃O₄ magnetic nanocomposite film/fabric

Wang

Feng

et al. 2022

RSC Adv.

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“…In each day within the 4-day interval, the MTDRs were observed under an inverted microscope and the cells were harvested using TrypLE Select enzymes (GIBCO, 12563-011) from ThermoFisher Scientific (Waltham, MA, USA). The cells were counted according to counting chambers in a hemacytometer [ 62 , 63 ]. The resulted data were in the form of viability rates, which were the percentages of the viable cells per total cultured cells.…”

Section: Methodsmentioning

confidence: 99%

Anatomically and Biomechanically Relevant Monolithic Total Disc Replacement Made of 3D-Printed Thermoplastic Polyurethane

Nadhif

Ghiffary²,

Irsyad

et al. 2022

Polymers

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Various implant treatments, including total disc replacements, have been tried to treat lumbar intervertebral disc (IVD) degeneration, which is claimed to be the main contributor of lower back pain. The treatments, however, come with peripheral issues. This study proposes a novel approach that complies with the anatomical features of IVD, the so-called monolithic total disc replacement (MTDR). As the name suggests, the MTDR is a one-part device that consists of lattice and rigid structures to mimic the nucleus pulposus and annulus fibrosus, respectively. The MTDR can be made of two types of thermoplastic polyurethane (TPU 87A and TPU 95A) and fabricated using a 3D printing approach: fused filament fabrication. The MTDR design involves two configurations—the full lattice (FLC) and anatomy-based (ABC) configurations. The MTDR is evaluated in terms of its physical, mechanical, and cytotoxicity properties. The physical characterization includes the geometrical evaluations, wettability measurements, degradability tests, and swelling tests. The mechanical characterization comprises compressive tests of the materials, an analytical approach using the Voigt model of composite, and a finite element analysis. The cytotoxicity assays include the direct assay using hemocytometry and the indirect assay using a tetrazolium-based colorimetric (MTS) assay. The geometrical evaluation shows that the fabrication results are tolerable, and the two materials have good wettability and low degradation rates. The mechanical characterization shows that the ABC-MTDR has more similar mechanical properties to an IVD than the FLC-MTDR. The cytotoxicity assays prove that the materials are non-cytotoxic, allowing cells to grow on the surfaces of the materials.

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Synthesis and characterization of biodegradable and cytocompatible polyurethane-bovine-derived hydroxyapatite biomaterials

Cited by 11 publications

References 23 publications

New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

Preparation and performance study of a reactive polyurethane hot-melt adhesive/CS–Fe₃O₄ magnetic nanocomposite film/fabric

Anatomically and Biomechanically Relevant Monolithic Total Disc Replacement Made of 3D-Printed Thermoplastic Polyurethane

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Synthesis and characterization of biodegradable and cytocompatible polyurethane-bovine-derived hydroxyapatite biomaterials

Cited by 11 publications

References 23 publications

New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

New Star-Shaped Polyether-Pentols (PEPOs) for Fabrication of Crosslinked Polyurethanes—Synthesis and Characterization

Preparation and performance study of a reactive polyurethane hot-melt adhesive/CS–Fe3O4 magnetic nanocomposite film/fabric

Anatomically and Biomechanically Relevant Monolithic Total Disc Replacement Made of 3D-Printed Thermoplastic Polyurethane

Contact Info

Product

Resources

About

Preparation and performance study of a reactive polyurethane hot-melt adhesive/CS–Fe₃O₄ magnetic nanocomposite film/fabric