2012
DOI: 10.1557/opl.2012.283
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Synthesis and characterization of copolymeric micelles loaded with Taxol® as potential drug delivery systems for cancer treatment

Abstract: Taxol (Paclitaxel) is a very potent anticancer drug used in chemotherapy treatments. Due to its hydrophobic nature, toxic solubilizing agents are used to administer the drug via intravenously. However, this systemic administration is associated with toxic side effects and drug limited efficacy. An alternative to these problems are polymeric micelles. The effectiveness of this drug delivery system is related to its size, modification of pharmacokinetics, drug delivery control and toxicity reduction. In this stu… Show more

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