Synthesis and Characterization of Copper Oxide Nanoparticles (CuO NPs) using Mangifera indica Leaf Extract

Selvi, V. Senthamil; Velumani, A.; Banu, N. Nisha

doi:10.30799/jnst.240.19050411

Cited by 1 publication

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“…The broadening of peak indicates that the particles are poly-dispersed. 24,25 Fourier transform infrared spectroscopy (FTIR): The FTIR analysis is done in a range 4000 to 500 cm -1 . Figure 2 (b) shows four different peaks functional groups at 3432 cm -1 , 2919 cm -1 , 1637 cm -1 and 611 cm -1 involving in formation of Cu NPs shown in Figure 2 b (A).…”

Section: Biophysical Characterization Of Cu Npsmentioning

confidence: 99%

Green Synthesis of Copper Nanoparticles Using Leaf Extract of Ocimum sanctum and its Antimicrobial Activity

Zambare¹,

Survase²,

Kanase³

2022

Int J. Pharm. Investigation

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Recent development in the field of nanotechnology leads to production of metal nanoparticles by various methods. Among available methods, biological method is preferable because of its certain advantages like ecofriendly nature, convenient method, generates nontoxic products. 9 The biological approach to metal or metal oxide nanoparticle synthesis emphasises the use of bacteria, fungi, algae, yeast, and plant extracts as reducing agents for nanoparticle formation which support large-scale production and biocompatibility. 10,11 CuO NPs synthesis has gained a lot of attention because of its long-term viability, low cost, and ease of use. 12 Combining nanotechnology and biology has enormous potential for developing drugs to treat infectious diseases. 13 ABSTRACT Objectives: We reported a non-toxic, low-cost and environmentally friendly green synthesis technique for the manufacture of copper nanoparticles (Cu NPs) utilizing Ocimum sanctum (O. sanctum) leaf extract to prevent hospital-acquired and Methicillin-resistant pathogenic bacterial infections strains. Materials and Methods: The biogenic synthesis of Cu NPs via chemical precipitation method using O. sanctum phytochemical extract as stabilizing and reducing agent. Cu NPs syntheses are characterized using UV-visible spectroscopy (UV-vis spectroscopy), X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) to analyze and confirm size and nature of Cu NPs. Results: UV-vis spectroscopy of Cu NPs showed an absorption peak at 528 nm with calculated band gap 2.1 eV. XRD analysis indicates crystallite nature of Cu NPs having an average size 48 nm. FTIR showed involvement of O. sanctum extract biomolecules in capping process Cu NPs. The hexagonal morphology structure of Cu NPs nanoparticles is observed by SEM analysis. Cu NPs showed antibacterial activity against Staphylococcus aureus (38.66 ± 1.15 mm), Escherichia coli (43.33 ± 1.15 mm), Pseudomonas aeruginosa (21.66 ± 0.57 mm) and Proteus vulgaris (42.66± 0.57 mm). Conclusion: We report synthesis of simple, inexpensive and eco-friendly O. sanctum mediated Cu NPs. The biophysical characterization techniques used for analyze size, shape and nature of nanoparticles. The 32 ug/ml Cu NPs concentration showed excellent antimicrobial activity against Gram positive and Gram-negative bacteria. Cu NPs efficiently used to prevent Proteus vulgaris mediated infection.

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Section: Biophysical Characterization Of Cu Npsmentioning

confidence: 99%