Synthesis and characterization of fluorene tethered benzo[c]thiophene/benzo[c]selenophene analogs

Kumar, Naresh; Mohanakrishnan, Arasambattu K.

doi:10.1016/j.tet.2010.05.060

Cited by 20 publications

(2 citation statements)

References 46 publications

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“…In addition, we are devoted to the development of DPP‐based NIR dyes, with introduction of electron donors such as triphenylamine and 4‐dimethylaminobenzophenone onto the electron‐deficient DPP core to construct D–A–D structured dyes, which have much more potential for biological imaging and tumor therapy . Due to the strong absorption in the NIR window, organic dyes such as benzo[1,2‐ c ;4,5‐ c ′]bis[1,2,5]thiadiazole (BBT)‐based derivatives, perylene‐diimide (PDI)‐based dyes, benzo[ c ]heterocycles, xanthene dyes, etc. ( Figure ) are also beneficial for deep‐tissue light penetration.…”

Section: Current Organic Dyes For Nanomedicinementioning

confidence: 99%

Organic Dye Based Nanoparticles for Cancer Phototheranostics

Cai

Huang

et al. 2018

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Phototheranostics, which simultaneously combines photodynamic and/or photothermal therapy with deep-tissue diagnostic imaging, is a promising strategy for the diagnosis and treatment of cancers. Organic dyes with the merits of strong near-infrared absorbance, high photo-to-radical and/or photothermal conversion efficiency, great biocompatibility, ready chemical structure fine-tuning capability, and easy metabolism, have been demonstrated as attractive candidates for clinical phototheranostics. These organic dyes can be further designed and fabricated into nanoparticles (NPs) using various strategies. Compared to free molecules, these NPs can be equipped with multiple synergistic functions and show longer lifetime in blood circulation and passive tumor-targeting property via the enhanced permeability and retention effect. In this article, the recent progress of organic dye-based NPs for cancer phototheranostic applications is summarized, which extends the anticancer arsenal and holds promise for clinical uses in the near future.

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Section: Current Organic Dyes For Nanomedicinementioning

confidence: 99%

Organic Dye Based Nanoparticles for Cancer Phototheranostics

Cai

Huang

et al. 2018

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“…Aromatic heterocyclic compounds are widely studied from a synthetic point of view as building blocks [1,2], due to their applicability in the polymer [3,4] and food industries [5,6] and to their potential biological activity [7].…”

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confidence: 99%