2017
DOI: 10.1016/j.ejps.2016.09.019
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Synthesis and characterization of genistein conjugated with gold nanoparticles and the study of their cytotoxic properties

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Cited by 51 publications
(24 citation statements)
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“…A shift into the nano-scale causes a significant increase in the specific grain boundary area per unit volume. This in turn results in a remarkable increase of the reactivity of the material, adsorption, anti-microbiological, and anticancer activity [ 6 , 7 , 8 , 9 , 10 ]. Nanoparticles improve therapy efficacy by transporting the drug to the drug target, thus increasing treatment safety.…”
Section: Introductionmentioning
confidence: 99%
“…A shift into the nano-scale causes a significant increase in the specific grain boundary area per unit volume. This in turn results in a remarkable increase of the reactivity of the material, adsorption, anti-microbiological, and anticancer activity [ 6 , 7 , 8 , 9 , 10 ]. Nanoparticles improve therapy efficacy by transporting the drug to the drug target, thus increasing treatment safety.…”
Section: Introductionmentioning
confidence: 99%
“…One of the examples is the conjugate consisting of gold nanoparticles (AuNPs) and a pharmacologically active anticancer substance abiraterone (AB) or genistein (AuNPs-GE). The obtained results suggest that the complexes AuNPs with anticancer drugs can enhance their anticancer effect (32,33).…”
mentioning
confidence: 77%
“…These groups were proposed to chelate different metal ions by the following steps: (1) Adsorption onto the metal surface, (2) budding of NP, (3) aggregation, and (4) bioreduction [59]. The possible mechanism for genistein AuNPs was proposed as follows: (1) Transfer of the electron from genistein into the Au center, (2) reduction of the Au 3+ to Au 0 by genistein, and (3) further acted as a stabilizing agent to form a layer of negative ions leading to the formation of the AuNPs [71].…”
Section: Mechanisms Of Flavonoids-mediated Np Synthesismentioning
confidence: 99%