Abstract:This study investigated the antibacterial activity of nano-zinc oxide (ZnO) composite hydrogels on the types of mold organism that commonly affect bamboo. The nano-ZnO was produced via the in situ method in poly(N-isopropylacrylamide-co-acrylic acid) (P(NIPAm-co-AAc)) hydrogel. The structures and properties were characterized using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), differential scanning ca… Show more
“…8 Examining the diffractograms of NVP/ITA/CS-ZnO nanocomposites shows the presence of a broad peak at nearly 2-Theta: 20.24 o which corresponds to the amorphous crosslinked polymer matrix of NVP/ITA/CS in addition to the characteristic peaks of ZnO NPs at 2-Theta: 30.82 o , 34.56 o , 36.42 o , and 38.32 o . 20,21 Figure 5.XRD patterns of pure ZnO NPs and NVP/CS/ITA–ZnO nanocomposite hydrogel.…”
High swellable and biocompatible hydrogel composed of optimized composition of N-vinyl pyrrolidone (NVP), chitosan (CS), and itaconic acid (ITA) was prepared by the aid of gamma radiation. Certain optimized composition of the terpolymer hydrogel was used as a precursor for the preparation of its ZnO nanocomposite. The terpolymer hydrogel was characterized by various techniques FTIR, XRD, SEM, and TEM to evaluate the physical, chemical properties and morphology of the prepared hydrogels. FTIR proved the high interaction between the components of the terpolymer crosslinked hydrogel. Transmission Electron Microscope (TEM) confirmed the preparation of ZnO nanoparticles in the nanoscale with average particle size of 12.3 nm in the terpolymer matrix which is higher than the particle size of as prepared bare ZnO NPs. The gelability, crosslinking density, and high swellability of the prepared terpolymer hydrogel make it promising and suitable for application as wound dressing materials. In this respect, the NVP/ITA/CS terpolymer hydrogel first examined for controlled release of amoxicillin and second, the antibacterial test showed that neither Staphylococcus aureus nor Escherichia coli passed through the terpolymer nanocomposite hydrogel dressing; NVP/ITA/CS/ZnO nanocomposite hydrogel dressing could be considered a good blockade against bacteria. All results indicate that the nanocomposite hydrogel has great potential for biomedical applications, especially for wound dressings.
“…8 Examining the diffractograms of NVP/ITA/CS-ZnO nanocomposites shows the presence of a broad peak at nearly 2-Theta: 20.24 o which corresponds to the amorphous crosslinked polymer matrix of NVP/ITA/CS in addition to the characteristic peaks of ZnO NPs at 2-Theta: 30.82 o , 34.56 o , 36.42 o , and 38.32 o . 20,21 Figure 5.XRD patterns of pure ZnO NPs and NVP/CS/ITA–ZnO nanocomposite hydrogel.…”
High swellable and biocompatible hydrogel composed of optimized composition of N-vinyl pyrrolidone (NVP), chitosan (CS), and itaconic acid (ITA) was prepared by the aid of gamma radiation. Certain optimized composition of the terpolymer hydrogel was used as a precursor for the preparation of its ZnO nanocomposite. The terpolymer hydrogel was characterized by various techniques FTIR, XRD, SEM, and TEM to evaluate the physical, chemical properties and morphology of the prepared hydrogels. FTIR proved the high interaction between the components of the terpolymer crosslinked hydrogel. Transmission Electron Microscope (TEM) confirmed the preparation of ZnO nanoparticles in the nanoscale with average particle size of 12.3 nm in the terpolymer matrix which is higher than the particle size of as prepared bare ZnO NPs. The gelability, crosslinking density, and high swellability of the prepared terpolymer hydrogel make it promising and suitable for application as wound dressing materials. In this respect, the NVP/ITA/CS terpolymer hydrogel first examined for controlled release of amoxicillin and second, the antibacterial test showed that neither Staphylococcus aureus nor Escherichia coli passed through the terpolymer nanocomposite hydrogel dressing; NVP/ITA/CS/ZnO nanocomposite hydrogel dressing could be considered a good blockade against bacteria. All results indicate that the nanocomposite hydrogel has great potential for biomedical applications, especially for wound dressings.
“… [121] Liposomes DPPC, DSPE-PEG2000, MSPC Human lung large cell carcinoma F7 and TPT lipid film hydration and extrusion DLS, TEM, DSC i.v. [122] Artificial Extracellular Matrix HA, PNIPAM Tissue engineering — Graft polymerization H NMR, GPC with HPLC, Static contact angle by sessile drop method [123] Nanoaggregate Chitosan, Pluronic Hydrophobic drug delivery IMC Graft polymerization CAC, hydrodynamic size, and surface morphology by fluorescence spectroscopy, DLS, TEM In vitro [124] Nanoparticles NIPAAm, MAA Breast cancer Cur Free radical mechanism FTIR, H NMR, SEM In vitro [125] Nanocomposite Hydrogels ZnO, PNIPAm Anti-mold property — Radical polymerization method FTIR, TEM, DSC, DLS In vitro [126] Nanohybrid hydrogels Chitosan/ Graphene Breast cancer MTX Mixing FTIR, XRD, SEM In vitro [127] Injectable hydrogel Trimethyl chitosan/ tripolyphosphate Anemia EPO — DLS, SEM, digital rotary S.C. [128] Thermo-and pH-responsive Smart nanogel system PNIPAM Breast cancer ANST Solvent evaporation technique FTIR, DSC, XRD, TEM, AFM, DLS, optical spectroscopy, In vitro [129] Nanohydrogels Lactoferrin conjugated PNIPAM-a...…”
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