Cerium-doped lutetium yttrium oxyorthosilicate (Lu1-xYx)2SiO5:Ce crystal powders were synthesized by co-precipitation method. The properties of LYSO:Ce powders with Y3+ concentration and Ce3+ concentration were investigated using X-ray diffraction (XRD) and photoluminescence (PL). XRD results show that LYSO:Ce powder samples with different Y3+ concentration have the same crystal phase to compare with the crystal standard card. PL results show that LYSO:Ce powder has better luminescence performance when Y3+ concentration is 15 mol%. The luminescence and scintillation characteristics of the dosimeters were founded under X-ray irradiation with low dose rate of 2.284 Gy/min and compared with the dosimeter without LYSO:Ce powder material. The luminescence and scintillation properties of LYSO:Ce dosimeter indicate promising potential applications in real time remote low dose X-ray radiotherapy and radiation monitoring.