Synthesis and characterization of mixed ligand complexes of Zn(II) and Co(II) with amino acids: Relevance to zinc binding sites in zinc fingers

Reddy, P. Rabindra; Radhika, M.; Pallerla, Manjula

doi:10.1007/bf02709293

Cited by 51 publications

(23 citation statements)

References 29 publications

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“…Likewise, the H 2 O rocking vibration at 842 cm −1 was observed. The existence of Zn-N and Zn-Cl bonds was confirmed with absorptions at 491 and 283 cm −1 , respectively [43][44][45][46]. In contrast, the Raman spectrum of 3 showed the ν a (COO) vibration at 1592 cm −1 and ν(Cu-Cl) at 242 cm −1 , respectively.…”

Section: Spectroscopic Characterizationmentioning

confidence: 57%

Synthesis and structure of Zn(II) and Cu(II) complexes derived from 2-(aminomethyl)benzimidazole and glycine

Falcón-León

Tlahuext

Lechuga‐Islas

et al. 2014

Journal of Coordination Chemistry

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2014) Synthesis and structure of Zn(II) and Cu(II) complexes derived from 2-(aminomethyl)benzimidazole and glycine, Reactions of 2-(aminomethyl)benzimidazole di-hydrochloride (1·2HCl) and glycine with 3Zn (OH) 2 ·2ZnCO 3 or Cu(OAc) 2 ·H 2 O led to the synthesis of the quaternary coordination complexes 2 and 3. X-ray diffraction showed that these complexes are composed of 2a = [Zn(L)Cl(L′)] and 2b = [Zn(L)(H 2 O) 2 (L′)], and of 3a = [Cu(L)(H 2 O) 0.25 Cl(L′)] and 3b = [Cu(L)(H 2 O) 1.5 (L′)], respectively, where L = 2-(aminomethyl)benzimidazole and L′ = glycinate. Zn(II) in 2a has an intermediate geometry between a square-pyramid and a trigonal bipyramid structure.However, the geometry about the metal ion of units 2b, 3a, and 3b is distorted octahedral. Moreover, the supramolecular structures for 2 and 3 were assembled through N-H⋯O and O-H⋯Cl hydrogen bonds. In these complexes, H 2 O and N-H groups serve as proton donors, whereas chloride and C=O groups serve as proton acceptors. Also π-π stacking interactions between aromatic rings contribute to the stabilization of the supramolecular structure of 2 and 3. The Zn and Cu complexes were studied by infrared and Raman spectroscopy, which indicated that 2 and 3 have similar molecular structures in the solid state. Ultrasound activation at the end of the reaction was necessary to yield 2.

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Section: Spectroscopic Characterizationmentioning

confidence: 57%

Synthesis and structure of Zn(II) and Cu(II) complexes derived from 2-(aminomethyl)benzimidazole and glycine

Falcón-León

Tlahuext

Lechuga‐Islas

et al. 2014

Journal of Coordination Chemistry

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“…Magnetic susceptibility is recorded at room temperature on Faraday balance and the negative magnetic moments of complexes 1-3 suggest that the central metal ion is diamagnetic. As the complexes have no unpaired electrons, the above complexes are expected to have the tetrahedral geometry [32].…”

Section: Resultsmentioning

confidence: 99%

Synthesis and Characterization of Some Mixed Ligand Complexes of Zn(II) with 4, 4´- Bipyridine: Anti-inflammatory and Analgesic Activities of these Complexes

et al. 2014

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The mixed ligand complexes of Zn(II) with 4,4-bipyridine and some organic acids or amino acids were prepared in the solid form and characterized by elemental analysis, conductivity, magnetic moment measurement, IR, 1 H-NMR, 13 C-NMR and FAB + mass studies. To study anti-inflammatory and analgesic activities of these complexes, some Swiss albino mice of 5-7 weeks old were taken. One dose of the test compounds of 10 mg/kg was selected throughout the research work. The anti-inflammatory activity of the test compounds were determined by 'carrageenan induced mice paw edema inhibition' method. The analgesic activity was determined by 'acetic acid induced writhing' methods. These three compounds showed positive effects as anti-inflammatory and analgesic agents. Antiinflammatory and analgesic activities of the test compounds at 50 mg/kg were quite comparable to those of standard drugs at 10 mg/kg.

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“…The spectra for the Ni(II) and Cu(II) complexes of L-Ser show additional peaks at 597-605 nm due to d xy -d x2Ày2 transitions [47], indicating square planar type geometries for these complexes. Such d-d transitions are not exhibited by the Zn(II) complex due to the completely filled d-orbital of Zn(II) ion [48].…”

Section: Tablementioning

confidence: 97%

A combined experimental and quantum mechanical investigation on some selected metal complexes of l-serine with first row transition metal cations

Mandal

Das

Askari

2015

Journal of Molecular Structure

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Synthesis and characterization of mixed ligand complexes of Zn(II) and Co(II) with amino acids: Relevance to zinc binding sites in zinc fingers

Cited by 51 publications

References 29 publications

Synthesis and structure of Zn(II) and Cu(II) complexes derived from 2-(aminomethyl)benzimidazole and glycine

Synthesis and structure of Zn(II) and Cu(II) complexes derived from 2-(aminomethyl)benzimidazole and glycine

Synthesis and Characterization of Some Mixed Ligand Complexes of Zn(II) with 4, 4´- Bipyridine: Anti-inflammatory and Analgesic Activities of these Complexes

A combined experimental and quantum mechanical investigation on some selected metal complexes of l-serine with first row transition metal cations

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