Synthesis and Characterization of Molecularly Imprinted Polymer for the Removal/Extraction of Thymol from Spiked Blood Serum and River water

Abstract

Molecularly imprinted polymers (MIPs) were prepared by precipitation polymerization using thymol as a template molecule, acrylamide as a functional monomer and N,N-methylbisacrylamide as the crosslinker with a non-covalent approach. The polymers were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), fourier-transform infra red spectroscopy(FT-IR) and Brunauer-Emmett-Teller (BET). The SEM results depicted that the shape of polymer particles is spherical with uniform size (micro-meters). The BET results also showed better surface area, pore size and pore volume of MIP as compared to non-imprinted polymer (NIP). A series of parameters such as initial concentration, polymer dosage, effect of pH and slectivity with structural analogue were conducted. The selectivity of MIP towards thymol was appreciable as compared to its structural analogue gallic acid with a relative selectivity coefficient of 3.59. Finally, MIP has been successfully used for extraction of thymol from the spiked blood serum (84 %) and river water sample (98 %).

Selective removal of contaminants of emerging concern (CECs) from urban water cycle via Molecularly Imprinted Polymers (MIPs): Potential of upscaling and enabling reclaimed water reuse

“…However, it is not possible to establish a predicted trend for MIPs adsorption capacity toward target molecules with increasing or decreasing pH, as it depends on the most favorable chemical environment in which they are involved. Indeed, Bakhtiar et al [116] found a decrease in MIPs adsorption capacity of 20% toward 2-phenilphenol when the pH was different from 7. Again, Dai and Cortalezzi [117] reported an increase in the adsorption capacity of a MIPs sensor toward 2,4 di-nitrotoluene as the pH value increased.…”

Magnetic Core-Shell Nanoparticles Using Molecularly Imprinted Polymers for Zearalenone Determination

“…According to the approach used to prepare these MIPs, we can find up to three families [ 29 ]. First, the non-covalent imprinting approach: this procedure is based on relatively weak interactions such as electrostatic and hydrophobic interactions, hydrogen bonding or π-π bonding established between the template and structural polymer [ 30 , 31 , 32 , 33 ]. In second place, the covalent approach is based on covalent bond formation between the template molecule and the functional monomer before polymerization; once the polymer has been synthesized, the template molecule is extracted from the 3D-network disrupting the covalent bonds.…”