Synthesis and characterization of poly(alkyl α , L-glutamate-co-ethylene oxide)

Abstract

Rod-coil amphiphilic block copolymers, PALG-PEOs, poly(alkyl α, L-glutamate-co-ethylene oxide)s, were successfully synthesized in three steps: 1) esterification of L-glutamic acid, 2) synthesis of γ-alkyl L-gultamate N-carboxyanhydride, and 3) polymerization of NCA monomers. These molecules form polymeric micelles with the hydrophobic core and hydrophilic corona in aqueous solution, which were characterized by light scattering and static fluorescence measurement.

Hierarchical Assembly of PEG-b-Polypeptide Hybrid Block Copolymers on Graphite

“…Syntheses. The di- and triblock PEG and PSLG copolymer samples were prepared by ring-opening polymerization of SLG-NCA initiated by MPEG-NH 2 and NH 2 -PEG-NH 2 . Here is an example for the synthesis of diblock copolymer, PEG- b -PSLG.…”